Z Darzynkiewicz
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Explore the profile of Z Darzynkiewicz including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Halicka H, Ardelt B, Juan G, Mittelman A, Chen S, Traganos F, et al.
Int J Oncol
. 2011 Apr;
11(3):437-48.
PMID: 21528230
A herbal preparation denoted PC SPES(R) is available in 'natural food' or 'health food' stores in the United States. This mixture (patent pending, US Serial number 08/697,920) consists of extracts...
12.
Juan G, Darzynkiewicz Z
Curr Protoc Cytom
. 2008 Sep;
Chapter 7:Unit 7.9.
PMID: 18770736
Cyclins are key components of the cell cycle machinery. This unit describes techniques associated with measurement of these transiently expressed molecules and focusses on the combination of cell cycle analysis...
13.
Darzynkiewicz Z, Juan G
Curr Protoc Cytom
. 2008 Sep;
Chapter 7:Unit 7.8.
PMID: 18770735
This unit provides a detailed method for evaluating in situ DNA denaturation by flow cytometry. The principal technique is based upon the metachromatic properties of acridine orange. This technique has...
14.
Darzynkiewicz Z, Juan G
Curr Protoc Cytom
. 2008 Sep;
Chapter 7:Unit 7.7.
PMID: 18770734
During the past two decades, the techniques of analysis of cell cycle kinetics based upon the flow cytometric detection of BrdU incorporation have replaced the cumbersome autoradiographic methodology utilizing tritiated...
15.
Darzynkiewicz Z, Juan G
Curr Protoc Cytom
. 2008 Sep;
Chapter 7:Unit 7.5.
PMID: 18770732
This unit presents the most common methods of DNA content analysis. The techniques differ primarily in the mode of cell permeabilization (detergents versus prefixation with alcohol) and composition of the...
16.
Darzynkiewicz Z, Juan G
Curr Protoc Cytom
. 2008 Sep;
Chapter 7:Unit 7.4.
PMID: 18770731
This unit describes a method for identifying apoptotic cells based on in situ detection of DNA strand breaks. Correlated analysis of DNA content and DNA strand breaks allows one not...
17.
Darzynkiewicz Z, Juan G
Curr Protoc Cytom
. 2008 Sep;
Chapter 7:Unit 7.1.
PMID: 18770721
This unit discusses the general applicability of nucleic-acid analytical methods in both basic and clinical research. After immunophenotyping, analysis of nucleic acids is perhaps the most common application of flow...
18.
Ardelt W, Shogen K, Darzynkiewicz Z
Curr Pharm Biotechnol
. 2008 Aug;
9(3):215-25.
PMID: 18673287
Rana pipiens oocytes contain two homologues of pancreatic ribonuclease A that are cytostatic and cytotoxic to human cancer cells. Extensively studied Onconase is in advanced Phase IIIb clinical trials against...
19.
Darzynkiewicz Z, Juan G, Bedner E
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 8:Unit 8.4.
PMID: 18228389
This unit describes assays used to determine the distribution of a population of cells to the different stages of the cell cycle as analyzed by flow cytometry. Staining the DNA...
20.
Ardelt B, Juan G, Burfeind P, Salomon T, Wu J, Hsieh T, et al.
Int J Oncol
. 2007 Aug;
31(3):663-9.
PMID: 17671695
Onconase (ONC), an antitumor ribonuclease from oocytes of a frog Rana pipiens, capable of inducing apoptosis in many cell lines is synergistic with several other anticancer drugs. Since cytotoxic effects...