Z Borok
Overview
Explore the profile of Z Borok including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
926
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Recent Articles
1.
Zhou B, Stueve T, Mihalakakos E, Miao L, Mullen D, Wang Y, et al.
BMC Genomics
. 2021 Dec;
22(1):906.
PMID: 34922464
Background: Disruption of alveolar epithelial cell (AEC) differentiation is implicated in distal lung diseases such as chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and lung adenocarcinoma that impact morbidity and...
2.
Debebe A, Medina V, Chen C, Mahajan I, Jia C, Fu D, et al.
Oncogene
. 2017 Jul;
36(43):6020-6029.
PMID: 28671671
Obesity confers an independent risk for carcinogenesis. In the liver, steatosis often proceeds cancer formation; however, the mechanisms by which steatosis promotes carcinogenesis is unknown. We hypothesize that steatosis alters...
3.
Smith K, Zhou B, Avdulov S, Benyumov A, Peterson M, Liu Y, et al.
Sci Rep
. 2015 Dec;
5:18233.
PMID: 26678431
The epithelial to mesenchymal transition (EMT) imparts disease-defining properties to epithelial cells in cancer and organ fibrosis. Prior studies identify EMT control points at the level of transcription and translation,...
4.
Lin H, Lin S, Chung Y, Vonderfecht S, Camden J, Flodby P, et al.
Cell Death Dis
. 2014 Oct;
5:e1478.
PMID: 25341032
Autophagy maintains cell and tissue homeostasis through catabolic degradation. To better delineate the in vivo function for autophagy in adaptive responses to tissue injury, we examined the impact of compromised...
5.
Morgan-Bathke M, Lin H, Chibly A, Zhang W, Sun X, Chen C, et al.
J Dent Res
. 2013 Jul;
92(10):911-7.
PMID: 23884556
Autophagy is a catabolic pathway utilized to maintain a balance among the synthesis, degradation, and recycling of cellular components, thereby playing a role in cell growth, development, and homeostasis. Previous...
6.
Felton V, Borok Z, Willis B
Am J Physiol Lung Cell Mol Physiol
. 2009 Aug;
297(5):L805-12.
PMID: 19648289
The ability of transforming growth factor-beta1 (TGF-beta1) to induce epithelial-mesenchymal transition (EMT) in alveolar epithelial cells (AEC) in vitro and in vivo, together with the demonstration of EMT in biopsies...
7.
Kemp P, Kim K, Borok Z, Crandall E
J Physiol
. 2001 Nov;
536(Pt 3):693-701.
PMID: 11691865
1. Alveolar epithelial type II pneumocytes were isolated and purified from adult rat lung by elastase digestion and differential adhesion, and cultured in serum-free medium for approximately 2 days on...
8.
Borok Z, Brody S, You Y, Zhou B, Li X, Cannon P, et al.
J Virol
. 2001 Nov;
75(23):11747-54.
PMID: 11689655
We investigated the use of lentivirus vectors for gene transfer to quiescent alveolar epithelial cells. Primary rat alveolar epithelial cells (AEC) grown on plastic or as polarized monolayers on tissue...
9.
Roum J, Aledia A, Carungcong L, Kim K, Borok Z
J Appl Physiol (1985)
. 2001 Jul;
91(2):748-54.
PMID: 11457790
Exposure to high fractional inspired oxygen for 24 h increases permeability of the alveolar epithelium, contributing to the clinical manifestations of oxygen toxicity. Utilizing a model of the alveolar epithelium...
10.