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Yuyan Xiong

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Articles 52
Citations 4019
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Recent Articles
1.
Huo Z, Zhang S, Su G, Cai Y, Chen R, Jiang M, et al.
Int J Mol Sci . 2025 Jan; 26(2). PMID: 39859484
Breast cancer (BC) subtypes exhibit distinct epigenetic landscapes, with triple-negative breast cancer (TNBC) lacking effective targeted therapies. This study investigates histone biomarkers and therapeutic vulnerabilities across BC subtypes. The immunohistochemical...
2.
Li J, Li Y, Song G, Wang H, Zhang Q, Wang M, et al.
Mater Today Bio . 2025 Jan; 30():101396. PMID: 39802826
Organoids, exhibiting the capability to undergo differentiation in specific in vitro growth environments, have garnered significant attention in recent years due to their capacity to recapitulate human organs with resemblant...
3.
Liu W, Gui R, Li Y, Li M, Lei Z, Jin Y, et al.
Phytother Res . 2024 Nov; 39(1):246-263. PMID: 39523692
Insulin resistance (IR) is a central pathophysiological process underlying numerous chronic metabolic disorders, including type 2 diabetes and obesity. Lycii Cortex, a widely used traditional Chinese herb, has demonstrated potential...
4.
Gui R, Ren Y, Wang Z, Li Y, Wu C, Li X, et al.
Obes Rev . 2024 Aug; 25(11):e13818. PMID: 39191434
Interleukin-18 (IL-18), a potent and multifunctional pro-inflammatory cytokine, plays a critical role in regulating β-cell failure, β-cell death, insulin resistance, and various complications of diabetes mellitus (DM). It exerts its...
5.
Li Y, Cui Y, Wang Z, Wang L, Yu Y, Xiong Y
Front Immunol . 2024 Aug; 15:1419133. PMID: 39165353
Introduction: Gastric cancer (GC) remains a major global health threat ranking as the fifth most prevalent cancer. Hypoxia, a characteristic feature of solid tumors, significantly contributes to the malignant progression...
6.
Wang J, Gui R, Li Y, Li Z, Li Z, Liu S, et al.
Biochim Biophys Acta Mol Cell Res . 2024 Aug; 1871(7):119822. PMID: 39159685
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by chronic ovulation dysfunction and overproduction of androgens. Women with PCOS are commonly accompanied by insulin resistance (IR), which can...
7.
Lv Z, Ren Y, Li Y, Niu F, Li Z, Li M, et al.
Mol Med . 2024 Aug; 30(1):124. PMID: 39138413
Background: Obesity is well-established as a significant contributor to the development of insulin resistance (IR) and diabetes, partially due to elevated plasma saturated free fatty acids like palmitic acid (PA)....
8.
Zhang X, Chen R, Huo Z, Li W, Jiang M, Su G, et al.
Cancer Cell Int . 2024 Jul; 24(1):225. PMID: 38951894
Background: Despite the improved survival observed in PD-1/PD-L1 blockade therapy, a substantial proportion of cancer patients, including those with non-small cell lung cancer (NSCLC), still lack a response. Methods: Transcriptomic...
9.
Zhang Y, Ren Y, Li X, Li M, Fu M, Zhou W, et al.
Int J Biol Macromol . 2024 May; 271(Pt 2):132473. PMID: 38795886
Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) serve as transcriptional co-activators that dynamically shuttle between the cytoplasm and nucleus, resulting in either the suppression or enhancement of...
10.
Wang Y, Ma X, Guo J, Li Y, Xiong Y
J Orthop Surg Res . 2023 Dec; 18(1):968. PMID: 38102657
Background: Osteonecrosis of the femoral head (ONFH) is a disease with a high disability rate, and genetic factors are closely related to its pathogenesis. This study aimed to investigate the...