Yutaka Hashimoto
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Explore the profile of Yutaka Hashimoto including associated specialties, affiliations and a list of published articles.
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54
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1397
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Recent Articles
1.
Hashimoto Y, Kano O, Ebihara S
Geriatr Gerontol Int
. 2022 Sep;
22(10):883-888.
PMID: 36071029
Aim: Although older people are at an increased risk of developing delirium during hospitalization, no definitive screening tools exist to predict the condition. This study aimed to examine the effectiveness...
2.
Shi W, Sheng X, Dorr K, Hutton J, Emerson J, Davies H, et al.
Dev Cell
. 2021 Oct;
56(21):3019-3034.e7.
PMID: 34655525
Sex disparities in cardiac homeostasis and heart disease are well documented, with differences attributed to actions of sex hormones. However, studies have indicated sex chromosomes act outside of the gonads...
3.
Hashimoto Y, Shiina M, Maekawa S, Kato T, Shahryari V, Kulkarni P, et al.
PLoS One
. 2021 Sep;
16(9):e0253877.
PMID: 34587154
Catechol-estrogens can cause genetic mutations and to counteract their oncogenicity, the catechol-O-methyltransferase (COMT) gene is capable of neutralizing these reactive compounds. In this study, we determined the functional effects and...
4.
Shiina M, Hashimoto Y, Kulkarni P, Dasgupta P, Shahryari V, Yamamura S, et al.
BMC Cancer
. 2021 Sep;
21(1):1028.
PMID: 34525952
Background: Prostate cancer is one of the most commonly diagnosed cancers among men. African Americans (AA) are at an increased risk of developing prostate cancer compared to European Americans (EA)....
5.
Kulkarni P, Dasgupta P, Hashimoto Y, Shiina M, Shahryari V, Tabatabai Z, et al.
Cancer Res
. 2021 Jan;
81(6):1500-1512.
PMID: 33500248
Metastasis is the leading cause of mortality from kidney cancer, and understanding the underlying mechanism of this event will provide better strategies for its management. Here we investigated the biological,...
6.
Shirane M, Shoji H, Hashimoto Y, Katagiri H, Kobayashi S, Manabe T, et al.
Mol Brain
. 2020 Nov;
13(1):146.
PMID: 33172474
Protrudin is a protein that resides in the membrane of the endoplasmic reticulum and is highly expressed in the nervous system. Although mutations in the human protrudin gene (ZFYVE27, also...
7.
Kulkarni P, Dasgupta P, Bhat N, Hashimoto Y, Saini S, Shahryari V, et al.
Toxicol Appl Pharmacol
. 2020 Nov;
409:115308.
PMID: 33129824
This study investigated the role of the PI3K/Akt pathway in cadmium (Cd) induced malignant transformation of normal prostate epithelial (PWR1E and RWPE1) cells. Both PWR1E and RWPE1 cells were exposed...
8.
Dasgupta P, Kulkarni P, Majid S, Hashimoto Y, Shiina M, Shahryari V, et al.
Cell Death Dis
. 2020 Aug;
11(8):660.
PMID: 32814766
The molecular heterogeneity of renal cell carcinoma (RCC) complicates the therapeutic interventions for advanced metastatic disease and thus its management remains a significant challenge. This study investigates the role of...
9.
Dasgupta P, Kulkarni P, Bhat N, Majid S, Shiina M, Shahryari V, et al.
Toxicol Appl Pharmacol
. 2020 Jun;
401:115102.
PMID: 32512071
Purpose: Cadmium (Cd) is reported to be associated with carcinogenesis. The molecular mechanisms associated with Cd-induced prostate cancer (PCa) remain elusive. Materials And Methods: RWPE1, PWR1E and DU 145 cells...
10.
Kinoshita N, Hashimoto Y, Yasue N, Suzuki M, Cristea I, Ueno N
Cell Rep
. 2020 Mar;
30(11):3875-3888.e3.
PMID: 32187556
Physical forces generated by tissue-tissue interactions are a critical component of embryogenesis, aiding the formation of organs in a coordinated manner. In this study, using Xenopus laevis embryos and phosphoproteome...