Yusuke Tsubokou
Overview
Explore the profile of Yusuke Tsubokou including associated specialties, affiliations and a list of published articles.
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10
Citations
109
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Recent Articles
1.
Harada K, Fujimoto H, Tsubokou Y, Takeda K
Nihon Rinsho
. 2012 Apr;
69 Suppl 7:615-21.
PMID: 22519061
No abstract available.
2.
Kobayashi N, Yoshida K, Nakano S, Ohno T, Honda T, Tsubokou Y, et al.
Hypertension
. 2006 Mar;
47(4):671-9.
PMID: 16505212
Aldosterone may play a pivotal role in the pathophysiology of heart failure. To elucidate the beneficial cardioprotective mechanism of eplerenone, a novel selective aldosterone blocker, we hypothesized that eplerenone stimulates...
3.
Kobayashi N, Honda T, Yoshida K, Nakano S, Ohno T, Tsubokou Y, et al.
Atherosclerosis
. 2005 Oct;
187(1):92-100.
PMID: 16214149
To elucidate the molecular mechanisms of the cardioprotective effect of angiotensin-converting enzyme (ACE) inhibitors, we evaluated whether the effect of quinapril involved in bradykinin-endothelial nitric oxide synthase (eNOS) and oxidative...
4.
Kobayashi N, Hara K, Tojo A, Onozato M, Honda T, Yoshida K, et al.
Hypertension
. 2005 Feb;
45(4):538-44.
PMID: 15710785
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) may play an important role in atherosclerosis by inducing leukocyte adhesion molecules, such as intercellular and vascular cell adhesion molecule-1 (intercellular adhesion molecule-1 [ICAM-1],...
5.
Kobayashi N, Yoshida K, Mita S, Honda T, Hara K, Nakano S, et al.
J Hypertens
. 2004 Jun;
22(7):1397-402.
PMID: 15201557
Objective: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) and vascular endothelial growth factor (VEGF) may play key roles in atherosclerosis, and have been shown to regulate nitric oxide (NO) production. However,...
6.
Horinaka S, Kobayashi N, Yabe A, Asakawa H, Yagi H, Mori Y, et al.
Cardiovasc Drugs Ther
. 2004 Apr;
18(1):13-22.
PMID: 15115899
Nicorandil is an adenosine triphosphate sensitive K (K-ATP) channel opener and a nitric oxide donor. K-ATP channels and nitric oxide are important factors in ischemic preconditioning, which in turn suppresses...
7.
Kobayashi N, Mita S, Yoshida K, Honda T, Kobayashi T, Hara K, et al.
Hypertension
. 2003 Oct;
42(5):1004-13.
PMID: 14557279
Vascular cell adhesion molecule-1 (VCAM-1) and reactive oxygen species play critical roles in early atherogenesis, and nitric oxide (NO) is an important regulator of the cardiovascular system. Although celiprolol, a...
8.
Tsubokou Y, Kobayashi N, Mita S, Yoshida K, Matsuoka H
Eur J Pharmacol
. 2002 Dec;
457(2-3):85-93.
PMID: 12464353
We evaluated the cardioprotective effects of long-term treatment with celiprolol (for 5 weeks), a specific beta(1)-adrenoceptor antagonist with a weak beta(2)-adrenoceptor agonist action, on endothelin-1 and transforming growth factor (TGF)-beta(1)...
9.
Kobayashi N, Nakano S, Mori Y, Mita S, Kobayashi T, Honda T, et al.
Hypertens Res
. 2002 Jun;
25(2):211-9.
PMID: 12047037
We evaluated the protective effects of long-term treatment with betaxolol, a specific beta-antagonist, on platelet-derived growth factor (PDGF) A-chain and transforming growth factor (TGF)-beta1 gene expression in the left ventricle...
10.
Kobayashi N, Nakano S, Mita S, Kobayashi T, Honda T, Tsubokou Y, et al.
J Pharmacol Exp Ther
. 2002 Apr;
301(2):459-66.
PMID: 11961044
Angiotensin II (Ang II) is a potent stimulator of plasminogen activator inhibitor-1 (PAI-1) expression, which is an important regulator of pathogenesis of atherosclerosis. Rho-kinase, a downstream target protein of small...