Yusuke Kamachi
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Explore the profile of Yusuke Kamachi including associated specialties, affiliations and a list of published articles.
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31
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1288
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Recent Articles
11.
Iwafuchi-Doi M, Yoshida Y, Onichtchouk D, Leichsenring M, Driever W, Takemoto T, et al.
Dev Biol
. 2010 Dec;
352(2):354-66.
PMID: 21185279
The transcription factor Sox2 is a core component of the pluripotency control circuits in the early embryo, and later controls many aspects of neural development. Here, we demonstrate that Sox2...
12.
B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo
Okuda Y, Ogura E, Kondoh H, Kamachi Y
PLoS Genet
. 2010 May;
6(5):e1000936.
PMID: 20463883
The B1 SOX transcription factors SOX1/2/3/19 have been implicated in various processes of early embryogenesis. However, their regulatory functions in stages from the blastula to early neurula remain largely unknown,...
13.
Kondoh H, Kamachi Y
Int J Biochem Cell Biol
. 2009 Sep;
42(3):391-9.
PMID: 19747562
Transcriptional regulatory functions of SOX proteins generally require the cooperation of partner factors that bind DNA in the vicinity of the SOX site. Each SOX-partner pair selects a specific group...
14.
Mon H, Sugahara R, Hong S, Lee J, Kamachi Y, Kawaguchi Y, et al.
Anal Biochem
. 2009 Jun;
392(2):180-2.
PMID: 19481053
Many biological processes are usually coupled to the formation of protein complexes. The yeast two-hybrid system is a powerful tool for analyzing protein-protein interactions. Different patterns of protein modifications, such...
15.
Kamachi Y, Iwafuchi M, Okuda Y, Takemoto T, Uchikawa M, Kondoh H
Proc Jpn Acad Ser B Phys Biol Sci
. 2009 Feb;
85(2):55-68.
PMID: 19212098
In higher vertebrates, the expression of Sox2, a group B1 Sox gene, is the hallmark of neural primordial cell state during the developmental processes from embryo to adult. Sox2 is...
16.
Ogura E, Okuda Y, Kondoh H, Kamachi Y
Dev Dyn
. 2009 Feb;
238(3):641-55.
PMID: 19191223
An enhancer trap-based GAL4-UAS system in zebrafish requires strong GAL4 activators with minimal adverse effects. However, the activity of yeast GAL4 is too low in zebrafish, while a fusion protein...
17.
Kanamori A, Toyama K, Kitagawa S, Kamehara A, Higuchi T, Kamachi Y, et al.
Gene
. 2008 Aug;
423(2):180-7.
PMID: 18678233
We analyzed molecular cascades of sex differentiation in medaka gonads by examining the transcriptional regulation of the oocyte-expressed gene, figalpha. We first confirmed that figalpha is one of the earliest...
18.
Kamachi Y, Okuda Y, Kondoh H
Genesis
. 2008 Jan;
46(1):1-7.
PMID: 18196596
Despite the broad use of morpholino antisense oligonucleotides (MO) to knockdown gene function in zebrafish embryos, the efficiency of this method has not been successfully assessed, particularly in the cases...
19.
Inoue M, Kamachi Y, Matsunami H, Imada K, Uchikawa M, Kondoh H
Genes Cells
. 2007 Sep;
12(9):1049-61.
PMID: 17825048
Sox2 is universally expressed in the neural and placodal primordia in early stage embryos, and this expression depends on various phylogenetically conserved enhancers having different regional and temporal specificities. The...
20.
Sato N, Kamachi Y, Kondoh H, Shima Y, Morohashi K, Horikawa R, et al.
Eur J Endocrinol
. 2007 Feb;
156(2):167-71.
PMID: 17287405
Objective: Heterozygous SOX2 mutations have recently been reported to cause isolated hypogonadotropic hypogonadism (HH), in addition to ocular and brain abnormalities. Here, we report a further case with a heterozygous...