Yusuf Y Deeni
Overview
Explore the profile of Yusuf Y Deeni including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
101
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0
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Recent Articles
1.
Kankia I, Paramasivan P, Elcombe M, Langdon S, Deeni Y
Explor Target Antitumor Ther
. 2022 Sep;
2(2):187-203.
PMID: 36046141
Aim: Nuclear factor erythroid 2-related factor 2 (NRF2) is a key component in the cell's response to oxidative and electrophilic stress and is a transcription factor regulating the expression of...
2.
Paramasivan P, Kankia I, Langdon S, Deeni Y
Cancer Drug Resist
. 2022 May;
2(3):490-515.
PMID: 35582567
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array of genes related to oxidative and electrophilic stress that promote and maintain redox homeostasis....
3.
Kankia I, Khalil H, Langdon S, Moult P, Bown J, Deeni Y
Oxid Med Cell Longev
. 2018 Feb;
2017:1864578.
PMID: 29410730
NF-E2-related factor 2 (NRF2) regulates the transcription of a battery of metabolic and cytoprotective genes. NRF2 and epidermal growth factor receptors (EGFRs/HERs) are regulators of cellular proliferation and determinants of...
4.
Kabir K, Deeni Y, Hapca S, Moore L, Spiers A
FEMS Microbiol Lett
. 2018 Jan;
365(4).
PMID: 29346641
Bacterial biosurfactants have a wide range of biological functions and biotechnological applications. Previous analyses had suggested a limit to their reduction of aqueous liquid surface tensions (γMin), and here we...
5.
McLaughlin K, Folorunso A, Deeni Y, Foster D, Gorbatiuk O, Hapca S, et al.
Res Microbiol
. 2017 Jan;
168(5):419-430.
PMID: 28131895
Although bacterial cellulose synthase (bcs) operons are widespread within the Proteobacteria phylum, subunits required for the partial-acetylation of the polymer appear to be restricted to a few γ-group soil, plant-associated...
6.
Khalil H, Langdon S, Goltsov A, Soininen T, Harrison D, Bown J, et al.
Oncotarget
. 2016 Oct;
7(46):75874-75901.
PMID: 27713148
Nuclear erythroid related factor-2 (NRF2) is known to promote cancer therapeutic detoxification and crosstalk with growth promoting pathways. HER2 receptor tyrosine kinase is frequently overexpressed in cancers leading to uncontrolled...
7.
Khalil H, Langdon S, Kankia I, Bown J, Deeni Y
Oxid Med Cell Longev
. 2016 Jan;
2016:4148791.
PMID: 26770651
NF-E2 related factor-2 (NRF2) is an essential transcription factor for multiple genes encoding antioxidants and detoxification enzymes. NRF2 is implicated in promoting cancer therapeutic resistance by its detoxification function and...
8.
Deeni Y, Ibbotson S, Woods J, Wolf C, Smith G
PLoS One
. 2013 Oct;
8(9):e75494.
PMID: 24086543
Background: There are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis. Psoralens are metabolised by cytochrome P450 enzymes (P450), and we hypothesised...
9.
Smith G, Wolf C, Deeni Y, Dawe R, Evans A, Comrie M, et al.
Lancet
. 2003 Apr;
361(9366):1336-43.
PMID: 12711469
Background: Treatment of common skin diseases such as psoriasis is complicated by differences between individuals in response to topical drug treatment and photochemotherapy. Individuality in hepatic expression of drug-metabolising enzymes...