Yury M Morozov
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Explore the profile of Yury M Morozov including associated specialties, affiliations and a list of published articles.
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38
Citations
1763
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Recent Articles
1.
Morozov Y, Rakic P
Cereb Cortex
. 2024 Jul;
34(7.
PMID: 39024157
The centrosome is the main microtubule organizing center in stem cells, and its mother centriole, anchored to the cell membrane, serves as the basal body of the primary cilium. Prolonged...
2.
Datta D, Perone I, Wijegunawardana D, Liang F, Morozov Y, Arellano J, et al.
Alzheimers Dement
. 2024 Mar;
20(4):2843-2860.
PMID: 38445818
Introduction: Tau phosphorylated at threonine-217 (pT217-tau) is a novel fluid-based biomarker that predicts onset of Alzheimer's disease (AD) symptoms, but little is known about how pT217-tau arises in the brain,...
3.
Datta D, Perone I, Wijegunawardana D, Liang F, Morozov Y, Arellano J, et al.
bioRxiv
. 2023 Nov;
PMID: 37986900
Introduction: pT217-tau is a novel fluid-based biomarker that predicts onset of Alzheimer's disease (AD) symptoms, but little is known about how pT217-tau arises in brain, as soluble pT217-tau is dephosphorylated...
4.
Datta D, Perone I, Morozov Y, Arellano J, Duque A, Rakic P, et al.
Cereb Cortex
. 2023 Oct;
33(24):11501-11516.
PMID: 37874022
Alzheimer's disease cortical tau pathology initiates in the layer II cell clusters of entorhinal cortex, but it is not known why these specific neurons are so vulnerable. Aging macaques exhibit...
5.
Morozov Y, Rakic P
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36901863
Mitochondrial malfunction and morphologic disorganization have been observed in brain cells as part of complex pathological changes. However, it is unclear what may be the role of mitochondria in the...
6.
Yang S, Datta D, Woo E, Duque A, Morozov Y, Arellano J, et al.
Mol Psychiatry
. 2022 Jun;
27(10):4252-4263.
PMID: 35732693
Glutamate carboxypeptidase-II (GCPII) expression in brain is increased by inflammation, e.g. by COVID19 infection, where it reduces NAAG stimulation of metabotropic glutamate receptor type 3 (mGluR3). GCPII-mGluR3 signaling is increasingly...
7.
Franjic D, Skarica M, Ma S, Arellano J, Tebbenkamp A, Choi J, et al.
Neuron
. 2021 Nov;
110(3):452-469.e14.
PMID: 34798047
The hippocampal-entorhinal system supports cognitive functions, has lifelong neurogenic capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To investigate neurogenic potential and cellular diversity, we profiled single-nucleus...
8.
Shibata M, Pattabiraman K, Muchnik S, Kaur N, Morozov Y, Cheng X, et al.
Nature
. 2021 Oct;
598(7881):489-494.
PMID: 34599306
The similarities and differences between nervous systems of various species result from developmental constraints and specific adaptations. Comparative analyses of the prefrontal cortex (PFC), a cerebral cortex region involved in...
9.
Komuro Y, Galas L, Morozov Y, Fahrion J, Raoult E, Lebon A, et al.
J Neurosci
. 2021 Aug;
41(42):8725-8741.
PMID: 34462307
Galanin, one of the most inducible neuropeptides, is widely present in developing brains, and its expression is altered by pathologic events (e.g., epilepsy, ischemia, and axotomy). The roles of galanin...
10.
Chen H, Zhang-Brotzge X, Morozov Y, Li Y, Wang S, Zhang H, et al.
JCI Insight
. 2021 Jul;
6(17).
PMID: 34324436
The creatine transporter (CrT) maintains brain creatine (Cr) levels, but the effects of its deficiency on energetics adaptation under stress remain unclear. There are also no effective treatments for CrT...