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Yupu Deng

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Articles 32
Citations 1343
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Recent Articles
1.
Cober N, Chaudhary K, Deng Y, Lee C, Rowe K, Abdelwahab H, et al.
Cytotherapy . 2025 Mar; PMID: 40088252
Pulmonary arterial hypertension (PAH) is triggered by pulmonary vascular endothelial cell apoptosis and microvascular loss. Therefore, therapies that can regenerate lost vasculature may offer therapeutic benefit. Endothelial colony-forming cells (ECFCs)...
2.
Seelemann E, Panchakshari S, Labana P, Wolverton M, Deng Y, Abdelwahab H, et al.
Am J Physiol Heart Circ Physiol . 2025 Jan; 328(3):H496-H508. PMID: 39873638
This study investigated the sexual dimorphism in right ventricle (RV) remodeling in right heart failure susceptible Fischer CDF rats using the pulmonary artery banding (PAB) model. Echocardiography and hemodynamic measurements...
3.
Cyr-Depauw C, Mizik I, Cook D, Lesage F, Vadivel A, Renesme L, et al.
Am J Respir Crit Care Med . 2024 Nov; 211(3):391-406. PMID: 39586004
The chronic lung disease bronchopulmonary dysplasia (BPD) remains the most common complication of extreme prematurity (<28 wk of gestation). Umbilical cord-derived mesenchymal stromal cells (UC-MSCs) represent an opportunity for autologous...
4.
Cober N, Rowe K, Deng Y, Benavente-Babace A, Courtman D, Godin M, et al.
J Extracell Biol . 2024 Jun; 2(6):e94. PMID: 38938918
Extracellular vesicles (EVs) secreted by stem and progenitor cells have significant potential as cell-free 'cellular' therapeutics. Yet, small EVs (<200 nm) are rapidly cleared after systemic administration, mainly by the...
5.
Cyr-Depauw C, Cook D, Mizik I, Lesage F, Vadivel A, Renesme L, et al.
Am J Respir Crit Care Med . 2024 Apr; 210(6):814-827. PMID: 38564376
The chronic lung disease bronchopulmonary dysplasia (BPD) is the most severe complication of extreme prematurity. BPD results in impaired lung alveolar and vascular development and long-term respiratory morbidity, for which...
6.
Godoy R, Cober N, Cook D, McCourt E, Deng Y, Wang L, et al.
Elife . 2023 Apr; 12. PMID: 37078698
We sought to define the mechanism underlying lung microvascular regeneration in a model of severe acute lung injury (ALI) induced by selective lung endothelial cell ablation. Intratracheal instillation of DT...
7.
Zelt J, Cadete V, Deng Y, Godoy R, Cuillerier A, Rowe K, et al.
Hypertension . 2022 Oct; 79(12):2774-2786. PMID: 36278405
Background: We explored the mechanism of maladaptive right ventricular (RV) remodeling in Fischer compared with Sprague-Dawley (SD) rats exposed to pressure overload. Methods: Pulmonary hypertension was induced by injection of...
8.
Lesage F, Deng Y, Renesme L, Sauvestre F, Ben Fadel N, Zhong S, et al.
Am J Respir Cell Mol Biol . 2021 Sep; 65(3):331-334. PMID: 34468292
No abstract available.
9.
Chaudhary K, Deng Y, Yang A, Cober N, Stewart D
J Am Heart Assoc . 2021 Jul; 10(15):e019488. PMID: 34315227
Background We have previously reported important strain differences in response to SU5416 (SU, a vascular endothelial growth factor receptor 2 inhibitor) in rats and have identified a specific colony of...
10.
Florian M, Wang J, Deng Y, Souza-Moreira L, Stewart D, Mei S
Stem Cell Res Ther . 2021 Mar; 12(1):184. PMID: 33726829
Background: Acute lung injury (ALI) and in its severe form, acute respiratory distress syndrome (ARDS), results in increased pulmonary vascular inflammation and permeability and is a major cause of mortality...