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Yunxuan Wang

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Articles 19
Citations 167
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Recent Articles
1.
Shan L, Wang W, Du L, Li D, Wang Y, Xie Y, et al.
Proc Natl Acad Sci U S A . 2024 Jul; 121(29):e2401834121. PMID: 38976739
Lung adenocarcinoma (LUAD) is the leading cause of cancer-related death worldwide, but the underlying molecular mechanisms remain largely unclear. The transcription factor (TF) specificity protein 1 (SP1) plays a crucial...
2.
Zhang Y, Wang Y, Li W, Liu S, Tan X, Zhang Q, et al.
ChemSusChem . 2024 May; 17(19):e202400487. PMID: 38807568
Effective fractionation of lignocelluosic biomass and subsequent valorization of all three major components under mild conditions were achieved. Pretreatment with acidified monophasic phenoxyethanol (EPH) efficiently removed 92.6 % lignin and...
3.
Li G, Su G, Wang Y, Wang W, Shi J, Li D, et al.
Commun Biol . 2023 Jun; 6(1):625. PMID: 37301913
G-quadruplexes (G4s) regulate DNA replication and gene transcription, and are enriched in promoters without fully appreciated functional relevance. Here we show high selection pressure on putative G4 (pG4) forming sequences...
4.
Yang Z, Yu J, Zhang J, Song H, Ye H, Liu J, et al.
Lab Chip . 2023 Apr; 23(9):2217-2227. PMID: 37067243
Microfluidic chambers are powerful tools for studying axonal mRNA localization and translation in neurons. In addition to specific manipulation and measurements of axons, microfluidic chambers are used for collecting axonal...
5.
Sai Bharadwaj A, Dev S, Zhuang J, Wang Y, Yoo C, Jeon B, et al.
Bioresour Technol . 2022 Nov; 368:128339. PMID: 36400274
Chemical pretreatment of lignocellulosic biomass (LCB) is essential for effective biological conversion in subsequent steps to produce biofuels or biochemicals. For effective pretreatment, high lignin content and its recalcitrant nature...
6.
Meng X, Wang Y, Conte A, Zhang S, Ryu J, Wie J, et al.
Bioresour Technol . 2022 Nov; 368:128280. PMID: 36368492
Biomass pretreatment is considered a key step in the 2nd generation biofuel production from lignocellulosic biomass. Research on conventional biomass pretreatment solvents has mainly been focused on carbohydrate conversion efficiency,...
7.
Huang C, Cheng J, Zhan Y, Liu X, Wang J, Wang Y, et al.
Bioresour Technol . 2022 Aug; 362:127771. PMID: 35964916
This study proposed a renewable deep eutectic solvent (DES) pretreatment using lignin-derived guaiacol as the hydrogen bond donor. The DES showed excellent biomass fractionation efficiency after the incorporation of trace...
8.
Wang Y, Meng X, Tian Y, Kim K, Jia L, Pu Y, et al.
ChemSusChem . 2021 Sep; 14(23):5235-5244. PMID: 34533890
Integrating multidisciplinary research in plant genetic engineering and renewable deep eutectic solvents (DESs) can facilitate a sustainable and economic biorefinery. Herein, we leveraged a plant genetic engineering approach to specifically...
9.
Hao A, Wang Y, Stovall D, Wang Y, Sui G
Int J Biol Sci . 2021 Sep; 17(13):3268-3280. PMID: 34512145
Cancer is a life-threatening disease, but cancer therapies based on epigenetic mechanisms have made great progress. Enhancer of zeste homolog 2 (EZH2) is the key catalytic component of Polycomb repressive...
10.
Zhang L, Yan T, Wang W, Wu Q, Li G, Li D, et al.
Biochem Biophys Res Commun . 2021 May; 561:93-100. PMID: 34020144
AKT1 plays a key role in cell growth and survival, and its activation in cancers is mediated by different mechanisms. In this study, we investigated the potential of G-quadruplex (G4)...