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Yunlei Yun

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Articles 12
Citations 38
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Recent Articles
1.
Sun J, Wang Z, Yun Y, Feng Y, Liu Z, Cui L, et al.
Cancer Cell Int . 2025 Mar; 25(1):97. PMID: 40089741
Background: Schisandrin B (Sch B) is an active component in Schisandra chinensis exerting anti-cancer effect, but the mechanism is obscure. This study was designed to explore the mechanism of Sch...
2.
Xia W, Chen S, Yun Y, Cui L, Wang Z, Hou J, et al.
J Pharmacol Toxicol Methods . 2024 Sep; 130:107565. PMID: 39321943
Objective: To establish a rapid and universal quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) method for measuring the exposure levels of five triazole antifungal drugs in human plasma, including voriconazole,...
3.
Wang Z, Li H, Yun Y, Wang H, Meng B, Mu Y, et al.
J Pharm Biomed Anal . 2022 Jul; 219:114938. PMID: 35850015
Objective: We sought to develop and optimize a targeted bile acids (BAs) metabolomics method based on a dynamic multiple reaction monitoring (dMRM) strategy and explored the dynamic alterations of BAs...
4.
Liu Y, Liu H, Xia Z, Wang Z, Yun Y, Zhang G, et al.
Int J Anal Chem . 2021 Sep; 2021:5524361. PMID: 34567122
Objective: To develop a new method for quantitatively analyzing six tyrosine kinase inhibitors (gefitinib, erlotinib, icotinib, afatinib, osimertinib, and crizotinib) used in the treatment of non-small cell lung cancer (NSCLC)...
5.
Ren X, Wang Z, Yun Y, Meng G, Zhang X, Ding H, et al.
Int J Anal Chem . 2019 Mar; 2019:1536532. PMID: 30853983
Objective: To establish and validate a simple, sensitive, and rapid liquid chromatography tandem mass spectrometry (LC-MS/MS) method for the determination of methotrexate (MTX) and its major metabolite 7-hydroxy-methotrexate (7-OH-MTX) in...
6.
Jiang W, Xia T, Yun Y, Li M, Zhang F, Gao S, et al.
J Chromatogr B Analyt Technol Biomed Life Sci . 2019 Jan; 1108:17-24. PMID: 30660838
Carbamazepine (CBZ) was considered as the drug of choice in the treatment for various forms of epilepsy, yet the non-negligible adverse effects of CBZ suspend as the major concern for...
7.
Gao S, Tao Z, Zhou J, Wang Z, Yun Y, Li M, et al.
J Anal Methods Chem . 2018 Jul; 2018:7967694. PMID: 30046507
Therapeutic drug monitoring for anticancer drugs could timely reflect drug exposure, and it was a powerful tool for adjusting and maintaining drug concentration into a reasonable range, so that an...
8.
Wang Z, Yun Y, Xie X, You C, Miao H, Zhang F, et al.
J Clin Lab Anal . 2017 Feb; 32(1). PMID: 28205314
Objectives: This study was designed to compare the performance of LC-MS/MS with chemiluminescent microparticle immunoassay (CMIA) for determination of VPA in epilepsy patients in the perspective of metabolites' hepatotoxicity. Method:...
9.
Xia T, Gao S, Shu C, Wen Y, Yun Y, Tao X, et al.
Clin Biochem . 2016 Oct; 49(18):1372-1378. PMID: 27693603
Objectives: To investigate potential interferences of two pre-analytical variables, the storage time and the vacutainer tube, on the quantification of 20 amino acids using a UHPLC-MS/MS method. Design And Methods:...
10.
Wei H, Miao H, Yun Y, Li J, Qian X, Wu R, et al.
Ther Drug Monit . 2014 Nov; 36(6):781-8. PMID: 25392942
Background: Wuzhi capsule (WZC) is an ethanol extract from the ripe fruit of Schisandra sphenanthera in traditional Chinese medicine that has long been used to treat viral and drug-induced hepatitis...