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Yun Kwon

Explore the profile of Yun Kwon including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 194
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Recent Articles
1.
Huynh T, Jang S, Ban Y, Lee E, Kim T, Kang I, et al.
JACS Au . 2024 Dec; 4(12):4821-4832. PMID: 39735922
Four new macrolides, spirosnuolides A-D (-, respectively), were discovered from the termite nest-derived sp. INHA29. Spirosnuolides A-D are 18-membered macrolides sharing an embedded [6,6]-spiroketal functionality inside the macrocycle and are...
2.
Kwon Y, Gottmann P, Wang S, Tissink J, Motzler K, Sekar R, et al.
J Hepatol . 2024 Jul; 82(1):18-27. PMID: 38977136
Background & Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease. Owing to limited available treatment options, novel pre-clinical models for target selection...
3.
Huynh T, Kim H, Lee J, Ban Y, Jang Y, Heo B, et al.
J Nat Prod . 2024 Mar; 87(3):591-599. PMID: 38442389
A new polyol polyketide, named retinestatin (), was obtained and characterized from the culture of a strain, which was isolated from a subterranean nest of the termite Morimoto. The planar...
4.
Huynh T, Bae E, Heo B, Lee J, An J, Kwon Y, et al.
Mar Drugs . 2023 Sep; 21(9). PMID: 37755113
Two new proton-deficient metabolites, tandocyclinones A and B ( and ), were discovered via the chemical profiling of the sp. strain TDH03, which was isolated from a marine sediment sample...
5.
Giroud M, Kotschi S, Kwon Y, Le Thuc O, Hoffmann A, Gil-Lozano M, et al.
EMBO Rep . 2023 Sep; 24(10):e57600. PMID: 37671834
Adipocytes are critical regulators of metabolism and energy balance. While white adipocyte dysfunction is a hallmark of obesity-associated disorders, thermogenic adipocytes are linked to cardiometabolic health. As adipocytes dynamically adapt...
6.
Shin D, Byun W, Kang S, Kang I, Bae E, An J, et al.
J Am Chem Soc . 2023 Aug; 145(36):19676-19690. PMID: 37642383
A targeted and logical discovery method was devised for natural products containing piperazic acid (Piz), which is biosynthesized from ornithine by l-ornithine -hydroxylase (KtzI) and - bond formation enzyme (KtzT)....
7.
Cui J, Ye S, Shin D, Cho I, Yun Kim H, Kwon Y, et al.
Mar Drugs . 2023 Feb; 21(2). PMID: 36827108
Two new glycosylated and succinylated macrocyclic lactones, succinyl glyco-oxydifficidin () and succinyl macrolactin O (), were isolated from a strain collected from an intertidal mudflat on Anmyeon Island in Korea....
8.
Sekar R, Motzler K, Kwon Y, Novikoff A, Julg J, Najafi B, et al.
Cell Metab . 2022 Dec; 34(12):2047. PMID: 36476936
No abstract available.
9.
Sekar R, Motzler K, Kwon Y, Novikoff A, Julg J, Najafi B, et al.
Cell Metab . 2022 Oct; 34(11):1824-1842.e9. PMID: 36243006
During mammalian energy homeostasis, the glucagon receptor (Gcgr) plays a key role in regulating both glucose and lipid metabolisms. However, the mechanisms by which these distinct signaling arms are differentially...
10.
Im J, Shin D, Ban Y, Byun W, Bae E, Lee D, et al.
Org Lett . 2022 Sep; 24(39):7188-7193. PMID: 36165456
A genomic and spectroscopic signature-based search revealed a cycloaromatized enediyne, jejucarboside A (), from a marine actinomycete strain. The structure of was determined as a new cyclopenta[]indene glycoside bearing carbonate...