Yuma T Ortiz
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Explore the profile of Yuma T Ortiz including associated specialties, affiliations and a list of published articles.
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10
Citations
223
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Recent Articles
1.
Ortiz Y, Shamir L, McMahon L, Wilkerson J
PLoS One
. 2024 Aug;
19(8):e0309398.
PMID: 39208033
For many cancer patients tumor burden negatively impacts quality of life due to associated pain onset. Neuropathic pain is commonly associated with late cancer stages, and is resultant of tumor...
2.
Shahbazi Nia S, Ortiz Y, Zuarth Gonzalez J, Shamir L, Frimpong-Manson K, Hossain M, et al.
ACS Pharmacol Transl Sci
. 2024 Mar;
7(3):654-666.
PMID: 38481688
Opioids represent the most extensive category of abused substances in the United States, and the number of fatalities caused by these drugs exceeds those associated with all other drug overdoses...
3.
Frimpong-Manson K, Ortiz Y, McMahon L, Wilkerson J
Front Mol Neurosci
. 2024 Mar;
17:1355281.
PMID: 38481473
The individual and global burden of migraine is of such significance that there are accelerated efforts to develop new therapies. New migraine therapeutics are needed to address the current deficiencies...
4.
Ortiz Y, Bilbrey J, Felix J, Kienegger E, Mottinelli M, Mukhopadhyay S, et al.
Pharmacol Rep
. 2023 May;
75(4):937-950.
PMID: 37243887
Background: For many chemotherapy patients peripheral neuropathy is a debilitating side effect. Mitragyna speciosa (kratom) contains the alkaloid mitragynine (MG), which produces analgesia in multiple preclinical pain models. In humans,...
5.
Ortiz Y, McMahon L, Wilkerson J
Front Pharmacol
. 2022 May;
13:881810.
PMID: 35529444
Cannabinoids, including those found in cannabis, have shown promise as potential therapeutics for numerous health issues, including pathological pain and diseases that produce an impact on neurological processing and function....
6.
Zainul Z, Ma B, Koka M, Wilkerson J, Ortiz Y, Kerosuo L, et al.
Sci Rep
. 2022 Mar;
12(1):3344.
PMID: 35228612
Incomplete functional recovery after peripheral nerve injury (PNI) often results in devastating physical disabilities in human patients. Despite improved progress in surgical and non-surgical approaches, achieving complete functional recovery following...
7.
Bilbrey J, Ortiz Y, Felix J, McMahon L, Wilkerson J
Psychopharmacology (Berl)
. 2021 Nov;
239(5):1475-1486.
PMID: 34846548
Pain is one of the most common reasons to seek medical attention, and chronic pain is a worldwide epidemic. Anecdotal reports suggest cannabis may be an effective analgesic. As cannabis...
8.
He Y, Koch R, Budamagunta V, Zhang P, Zhang X, Khan S, et al.
J Hematol Oncol
. 2020 Jul;
13(1):95.
PMID: 32677976
Background: Patients with advanced T cell lymphomas (TCLs) have limited therapeutic options and poor outcomes in part because their TCLs evade apoptosis through upregulation of anti-apoptotic Bcl-2 proteins. Subsets of...
9.
He Y, Zhang X, Chang J, Kim H, Zhang P, Wang Y, et al.
Nat Commun
. 2020 Apr;
11(1):1996.
PMID: 32332723
Small molecules that selectively kill senescent cells (SCs), termed senolytics, have the potential to prevent and treat various age-related diseases and extend healthspan. The use of Bcl-xl inhibitors as senolytics...
10.
He Y, Li W, Lv D, Zhang X, Zhang X, Ortiz Y, et al.
Aging Cell
. 2020 Feb;
19(3):e13117.
PMID: 32064756
The accumulation of senescent cells (SnCs) is a causal factor of various age-related diseases as well as some of the side effects of chemotherapy. Pharmacological elimination of SnCs (senolysis) has...