Yukio Ando
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Explore the profile of Yukio Ando including associated specialties, affiliations and a list of published articles.
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503
Citations
5374
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Recent Articles
1.
Fukunari A, Matsushita H, Furukawa T, Matsuzaki H, Tanaka H, Ogawa Y, et al.
Biochem Biophys Res Commun
. 2024 Nov;
737:150770.
PMID: 39500040
Transthyretin (TTR) is an amyloidogenic protein associated with TTR amyloidosis (ATTR). Dissociation of TTR tetramers into TTR monomers causes TTR misfolding, resulting in amyloid fibril formation and triggering the onset...
2.
Maruyama Saladini K, Koike H, Ueda M, Sekijima Y, Ando Y
Rinsho Shinkeigaku
. 2024 Sep;
64(10):708-713.
PMID: 39322556
Late-onset hereditary ATTR (ATTRv) amyloidosis in nonendemic areas takes long periods of time to diagnose in many cases because the clinical symptoms are varied and nonspecific with the family history...
3.
Morii M, Kubota S, Iimori M, Yokomizo-Nakano T, Hamashima A, Bai J, et al.
Leukemia
. 2024 May;
38(6):1275-1286.
PMID: 38734786
TIF1β/KAP1/TRIM28, a chromatin modulator, both represses and activates the transcription of genes in normal and malignant cells. Analyses of datasets on leukemia patients revealed that the expression level of TIF1β...
4.
Mizuguchi M, Nakagawa Y, Yokoyama T, Okada T, Fujii K, Takahashi K, et al.
J Med Chem
. 2024 Apr;
PMID: 38670538
Transthyretin amyloidosis is a fatal disorder caused by transthyretin amyloid aggregation. Stabilizing the native structure of transthyretin is an effective approach to inhibit amyloid aggregation. To develop kinetic stabilizers of...
5.
Nomura T, Misumi Y, Tasaki M, Obayashi K, Yamashita T, Ando Y, et al.
JAMA Neurol
. 2024 Feb;
PMID: 38407867
No abstract available.
6.
Ouchi K, Isono K, Ohya Y, Shiraki N, Tasaki M, Inomata Y, et al.
Heliyon
. 2024 Feb;
10(2):e24590.
PMID: 38312695
Hereditary transthyretin (TTR) amyloidosis (ATTRv amyloidosis) is autosomal dominant and caused by mutation of gene. Heterozygous ATTR Tyr114Cys (p.Tyr134Cys) amyloidosis is a lethal disease with a life expectancy of about...
7.
Watanabe T, Takihara Y, Jono H, Fujimoto T, Tasaki M, Isoguchi A, et al.
Biochem Biophys Res Commun
. 2023 Dec;
694:149397.
PMID: 38157582
The first small interfering RNA (siRNA) therapeutic received approval for hereditary transthyretin (ATTRv) amyloidosis, and the patients' lifespan extension by specific inhibition of hepatic synthesis of transthyretin (TTR) is expected....
8.
Yamaguchi A, Tasaki M, Ueda M, Ando Y, Naiki H
Pathol Int
. 2023 Dec;
74(2):68-76.
PMID: 38088470
Clinical presentation of systemic amyloidosis differs among subtypes, and accurate subtype classification is important for choosing the treatment. Amyloid transthyretin (ATTR) amyloidosis was the predominant among the recently consulted amyloidosis...
9.
Ueda M, Misumi Y, Nomura T, Tasaki M, Yamakawa S, Obayashi K, et al.
Ann Neurol
. 2023 Dec;
95(2):230-236.
PMID: 38053464
Hereditary transthyretin (ATTRv) amyloidosis is a rare, fatal systemic disease, associated with polyneuropathy and cardiomyopathy, that is caused by mutant transthyretin (TTR). In addition to liver transplantation, several groundbreaking disease-modifying...
10.
Masuda T, Misumi Y, Nomura T, Yamakawa S, Tasaki M, Obayashi K, et al.
Muscle Nerve
. 2023 Nov;
69(1):99-102.
PMID: 37960924
Introduction/aims: In the early stage, hereditary transthyretin (ATTRv) amyloidosis predominantly affects small nerve fibers, resulting in autonomic dysfunction and impaired sensation of pain and temperature. Evaluation of small fiber neuropathy...