Yuki Yamaguchi
Overview
Explore the profile of Yuki Yamaguchi including associated specialties, affiliations and a list of published articles.
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Articles
168
Citations
4216
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Recent Articles
1.
Fujioka M, Zagarzusem K, Iwasaki S, Sharma A, Watanabe K, Nakayama R, et al.
J Am Chem Soc
. 2024 Dec;
146(50):34324-34332.
PMID: 39626204
Intercalation reactions are highly dependent on the electronic and structural relationships between host and guest materials. It is difficult for divalent ions, such as Mg, to undergo intercalation reactions compared...
2.
Takino R, Yamaguchi Y, Maruno T, Ramadhani E, Furukawa M, Torisu T, et al.
Mol Ther Methods Clin Dev
. 2024 Dec;
32(4):101362.
PMID: 39624799
Recombinant adeno-associated virus (rAAV) is a small, nonenveloped virus vector that has attracted attention as a gene therapy platform. Several studies have revealed the stability characteristics of rAAV; however, its...
3.
Iwaki M, Kobayashi T, Nogami A, Ogawa Y, Imajo K, Sakai E, et al.
BMJ Open
. 2024 Nov;
14(11):e088862.
PMID: 39581726
Introduction: Non-alcoholic fatty liver disease, now known as metabolic dysfunction-associated steatotic liver disease (MASLD), is a phenotype of the metabolic syndrome in the liver and is clearly associated with metabolic...
4.
Nakatsuka R, Yamaguchi Y, Hirohata K, Shimojo S, Murakami M, Rocafort M, et al.
Anal Chem
. 2024 Oct;
96(42):17037-17046.
PMID: 39434662
Adeno-associated virus (AAV) vectors have attracted significant attention as the main platform for gene therapy. To ensure the safety and efficacy of AAV vectors when used as gene therapy drugs,...
5.
Noguchi K, Suzuki H, Abe R, Horiuchi K, Onoguchi-Mizutani R, Akimitsu N, et al.
Cell Rep
. 2024 Sep;
43(9):114734.
PMID: 39283744
Membrane-less subcellular compartments play important roles in various cellular functions. Although techniques exist to identify components of cellular bodies, a comprehensive method for analyzing both static and dynamic states has...
6.
Yamamoto N, Kitano S, Koyama T, Ikeda M, Mizugaki H, Narikiyo T, et al.
J Immunother Cancer
. 2024 Jul;
12(7.
PMID: 39053945
Background: Immunosuppressive conditions within the tumor microenvironment (TME) can allow tumors to evade the immune system, including by hampering programmed death ligand 1 (PD-L1) inhibitor activity. Interleukin (IL)-8 contributes to...
7.
Horino S, Ozaki A, Yamaguchi Y, Miyabayashi H, Aki H, Aizawa H, et al.
Arerugi
. 2024 Jul;
73(5):399-405.
PMID: 39010199
Background: The number of students with food allergies is on the increase, while the problems and burdens of school teachers and staff are not yet clear. Our study was designed...
8.
Kanai M, Ganbaatar B, Endo I, Ohnishi Y, Teramachi J, Tenshin H, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38891908
Chronic inflammation causes muscle wasting. Because most inflammatory cytokine signals are mediated via TGF-β-activated kinase-1 (TAK1) activation, inflammatory cytokine-induced muscle wasting may be ameliorated by the inhibition of TAK1 activity....
9.
Yamaguchi Y, Ishii K, Koizumi S, Sakaue H, Maruno T, Fukuhara M, et al.
Mol Ther Methods Clin Dev
. 2024 May;
32(2):101256.
PMID: 38774582
Glycosylation of biopharmaceuticals can affect their safety and efficacy. Glycans can occur on recombinant adeno-associated viruses (rAAVs) that are used for gene therapy; however, the types of glycans that attach...
10.
Ikeda T, Yamaguchi Y, Oyama H, Matsushita A, Tsunaka Y, Fukuhara M, et al.
Viruses
. 2024 Apr;
16(4).
PMID: 38675928
The higher-order structure (HOS) is a critical quality attribute of recombinant adeno-associated viruses (rAAVs). Evaluating the HOS of the entire rAAV capsid is challenging because of the flexibility and/or less...