Yuji Kajiwara
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Explore the profile of Yuji Kajiwara including associated specialties, affiliations and a list of published articles.
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24
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1346
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Recent Articles
1.
Kajiwara Y, Kuwana T, Inouye M
Dev Growth Differ
. 2023 Jun;
32(3):275-282.
PMID: 37281070
Chimaeric mice were produced by introducing dissociated embryonic cells of C57BL/6N mice into the embryos of Jcl: ICR albino mice at mid-gestation in utero. The patterns and the existence of...
2.
Craig 2nd R, Fox B, Hu C, Lexa K, Osipov M, Thottumkara A, et al.
J Med Chem
. 2022 Dec;
65(24):16290-16312.
PMID: 36469401
Dual leucine zipper kinase (DLK) and leucine zipper-bearing kinase (LZK) are regulators of neuronal degeneration and axon growth. Therefore, there is a considerable interest in developing DLK/LZK inhibitors for neurodegenerative...
3.
Darvish H, Azcona L, Tafakhori A, Mesias R, Ahmadifard A, Sanchez E, et al.
Sci Rep
. 2020 Jan;
10(1):968.
PMID: 31969655
Intellectual disability (ID), which presents itself during childhood, belongs to a group of neurodevelopmental disorders (NDDs) that are clinically widely heterogeneous and highly heritable, often being caused by single gene...
4.
James D, Kozol R, Kajiwara Y, Wahl A, Storrs E, Buxbaum J, et al.
Mol Autism
. 2019 Feb;
10:3.
PMID: 30733854
Background And Aims: Autism spectrum disorder (ASD) is currently estimated to affect more than 1% of the world population. For people with ASD, gastrointestinal (GI) distress is a commonly reported...
5.
Kajiwara Y, Wang E, Wang M, Sin W, Brennand K, Schadt E, et al.
Acta Neuropathol Commun
. 2018 Dec;
6(1):144.
PMID: 30577786
GJA1 (connexin43) has been predicted as the top key driver of an astrocyte enriched subnetwork associated with Alzheimer's disease (AD). In this study, we comprehensively examined GJA1 expression across 29...
6.
Drapeau E, Riad M, Kajiwara Y, Buxbaum J
eNeuro
. 2018 Oct;
5(3).
PMID: 30302388
Phelan-McDermid syndrome (PMS) is a rare genetic disorder in which one copy of the gene is missing or mutated, leading to a global developmental delay, intellectual disability (ID), and autism....
7.
Kerur N, Fukuda S, Banerjee D, Kim Y, Fu D, Apicella I, et al.
Nat Med
. 2017 Nov;
24(1):50-61.
PMID: 29176737
Geographic atrophy is a blinding form of age-related macular degeneration characterized by retinal pigmented epithelium (RPE) death; the RPE also exhibits DICER1 deficiency, resultant accumulation of endogenous Alu-retroelement RNA, and...
8.
Huang Q, Voloudakis G, Ren Y, Yoon Y, Zhang E, Kajiwara Y, et al.
FASEB J
. 2017 Sep;
32(1):243-253.
PMID: 28855274
Reduced cerebral glucose utilization is found in aged individuals and often is an early sign of neurodegeneration. Here, we show that under glucose deprivation (GD) conditions, decreased expression of presenilin...
9.
Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand K, et al.
Genome Med
. 2016 Nov;
8(1):104.
PMID: 27799057
Background: Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive cognitive impairment and neurodegeneration. However, despite extensive clinical and genomic studies, the molecular basis of AD...
10.
Kajiwara Y, McKenzie A, Dorr N, Gama Sosa M, Elder G, Schmeidler J, et al.
Hum Mol Genet
. 2016 Aug;
25(19):4315-4327.
PMID: 27516385
Recent studies have indicated that innate immune signalling molecules are involved in late-onset Alzheimer's disease (LOAD) risk. Amyloid beta (Aβ) accumulates in AD brain, and has been proposed to act...