Yuichi Niikura
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Explore the profile of Yuichi Niikura including associated specialties, affiliations and a list of published articles.
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20
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703
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Recent Articles
1.
Ito T, Osada A, Ohta M, Yokota K, Nishiyama A, Niikura Y, et al.
Sci Rep
. 2021 Dec;
11(1):24074.
PMID: 34912016
Sexual reproduction involves the creation of sex-dependent gametes, oocytes and sperm. In mammals, sexually dimorphic differentiation commences in the primordial germ cells (PGCs) in embryonic gonads; PGCs in ovaries and...
2.
Nishizawa T, Niikura Y, Akasaka K, Watanabe M, Kurai D, Amano M, et al.
BMC Infect Dis
. 2019 Sep;
19(1):761.
PMID: 31477059
Background: Aspiration pneumonia is a serious problem among elderly patients; it is caused by many risk factors including dysphagia, poor oral hygiene, malnutrition, and sedative medications. The aim of this...
3.
Niikura Y, Ishii T, Murakami J, Narita T, Fujita Y, Negishi H, et al.
Aging (Albany NY)
. 2019 Jan;
11(2):707-723.
PMID: 30677748
Reproductive organs play a pivotal role in asthma development and progression, especially in women. Endocrine environment changes associated with the menstrual cycle, pregnancy, and menopause can exacerbate the clinical features...
4.
McCallum M, Pru C, Niikura Y, Yee S, Lydon J, Peluso J, et al.
Endocrinology
. 2016 Jun;
157(9):3309-19.
PMID: 27309940
Progesterone (P4) is essential for female fertility. The objective of this study was to evaluate the functional requirement of the nonclassical P4 receptor (PGR), PGR membrane component 1, in regulating...
5.
Niikura Y, Ishii T, Hosoki K, Nagase T, Yamashita N
Biochem Biophys Res Commun
. 2015 Apr;
461(4):642-7.
PMID: 25912141
Biological differences between the sexes greatly impact the development and severity of pulmonary disorders such as emphysema. Recent studies have demonstrated crucial roles for osteopontin (OPN, also known as SPP1)...
6.
Narumoto O, Niikura Y, Ishii S, Morihara H, Okashiro S, Nakahari T, et al.
Biochem Biophys Res Commun
. 2013 Jul;
438(1):175-9.
PMID: 23876317
Acetylcholine (ACh) exerts various anti-inflammatory effects through α7 nicotinic ACh receptors (nAChRs). We have previously shown that secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), a positive allosteric modulator of...
7.
Woods D, White Y, Niikura Y, Kiatpongsan S, Lee H, Tilly J
Reprod Sci
. 2013 Mar;
20(5):524-35.
PMID: 23536570
Differentiating embryonic stem cells (ESCs) can form ovarian follicle-like structures in vitro, consisting of an oocyte-like cell surrounded by somatic cells capable of steroidogenesis. Using a dual-fluorescence reporter system in...
8.
Niikura Y, Niikura T, Wang N, Satirapod C, Tilly J
Aging (Albany NY)
. 2011 Jan;
2(12):999-1003.
PMID: 21212462
Through the use of parabiosis in mice, aging-related deterioration of skeletal muscle and liver has been linked to a loss of systemic factors that support adult stem or progenitor cell...
9.
Niikura Y, Niikura T, Tilly J
Aging (Albany NY)
. 2010 Feb;
1(12):971-8.
PMID: 20157580
Of all the major organ systems in the body, the ovaries of females are the first to exhibit impaired function with advancing age. Until recently, traditional thinking was that female...
10.
Tilly J, Niikura Y, Rueda B
Biol Reprod
. 2008 Aug;
80(1):2-12.
PMID: 18753611
Whether or not oogenesis continues in the ovaries of mammalian females during postnatal life was heavily debated from the late 1800s through the mid-1900s. However, in 1951 Lord Solomon Zuckerman...