Yu Togashi
Overview
Explore the profile of Yu Togashi including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
396
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Recent Articles
1.
Okuyama T, Tsuno T, Inoue R, Fukushima S, Kyohara M, Matsumura A, et al.
iScience
. 2025 Feb;
28(2):111856.
PMID: 39995864
The matricellular protein Fibulin-5 (Fbln5) is a secreted protein that is essential for elastic fiber formation, and pancreatic islets are usually surrounded by the extracellular matrix (ECM), which includes elastic...
2.
Ishizuka K, Shikino K, Takada N, Sakai Y, Ototake Y, Kobayashi T, et al.
BMC Med Educ
. 2025 Feb;
25(1):221.
PMID: 39934738
Background: Clinical reasoning skills are essential competencies for medical students; therefore, effective, evidence-informed teaching methodologies are needed worldwide. This study investigated the benefits of team-based learning (TBL) for developing the...
3.
Nishiyama K, Ono M, Tsuno T, Inoue R, Fukunaka A, Okuyama T, et al.
Endocrinology
. 2023 Jun;
164(8).
PMID: 37314160
Imeglimin and metformin act in metabolic organs, including β-cells, via different mechanisms. In the present study, we investigated the impacts of imeglimin, metformin, or their combination (Imeg + Met) on...
4.
Miyashita D, Inoue R, Tsuno T, Okuyama T, Kyohara M, Nakahashi-Oda C, et al.
iScience
. 2022 Dec;
25(12):105662.
PMID: 36505926
Obesity and diabetes are independent risk factors for death during sepsis. S100A8, an alarmin, is related to inflammation, obesity, and diabetes. Here, we examine the role of S100A8 in sepsis...
5.
Kyohara M, Miyashita D, Inoue R, Nishiyama K, Tsuno T, Okuyama T, et al.
PLoS One
. 2022 Nov;
17(11):e0276915.
PMID: 36331940
Plasma and liver SerpinB1 levels are elevated in mice with insulin resistance and promote β-cell proliferation in human islets. We measured serum SerpinB1 levels in Japanese subjects with or without...
6.
Shirakawa J, Togashi Y, Basile G, Okuyama T, Inoue R, Fernandez M, et al.
Cell Rep
. 2022 Oct;
41(1):111436.
PMID: 36198264
Prevention or amelioration of declining β cell mass is a potential strategy to cure diabetes. Here, we report the pathways utilized by β cells to robustly replicate in response to...
7.
Togashi Y, Miyashita D, Tsuno T, Inoue R, Okuyama T, Kyohara M, et al.
J Diabetes Investig
. 2022 Jul;
13(11):1861-1872.
PMID: 35818826
Aims/introduction: This study aimed to clarify the nature of the relationship between the abdominal aortic calcification (AAC) grade and the presence of cardiovascular diseases, and determine factors related to AAC...
8.
Inoue R, Tsuno T, Togashi Y, Okuyama T, Sato A, Nishiyama K, et al.
iScience
. 2022 Jul;
25(7):104603.
PMID: 35800776
Uncoupling protein 2 (UCP2), a mitochondrial protein, is known to be upregulated in pancreatic islets of patients with type 2 diabetes (T2DM); however, the pathological significance of this increase in...
9.
Li J, Inoue R, Togashi Y, Okuyama T, Satoh A, Kyohara M, et al.
Diabetes
. 2021 Sep;
71(3):424-439.
PMID: 34588186
The effects of imeglimin, a novel antidiabetes agent, on β-cell function remain unclear. Here, we unveiled the impact of imeglimin on β-cell survival. Treatment with imeglimin augmented mitochondrial function, enhanced...
10.
Terui S, Akamatsu R, Arai M, Inoue R, Okuyama T, Kyohara M, et al.
Diabetes Ther
. 2021 Sep;
12(11):2873-2889.
PMID: 34533697
Introduction: Dulaglutide is a long-acting glucagon-like peptide 1 receptor agonist that is administered once weekly for the treatment of type 2 diabetes. However, the immediate glucose-lowering effect of dulaglutide after...