Yu-Yuan Huang
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Explore the profile of Yu-Yuan Huang including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Wang R, Chen S, Fei C, Zhang Y, Chen K, Zhang W, et al.
Brain
. 2025 Mar;
PMID: 40036706
General paresis is a rare type of syphilis characterized by progressive cognitive impairment and psychiatric syndromes. It is often misdiagnosed because of its rarity and similarity with other diseases. We...
2.
Deng Y, You J, He Y, Zhang Y, Li H, Wu X, et al.
Cell
. 2024 Nov;
188(1):253-271.e7.
PMID: 39579765
Large-scale proteomics studies can refine our understanding of health and disease and enable precision medicine. Here, we provide a detailed atlas of 2,920 plasma proteins linking to diseases (406 prevalent...
3.
Huang Y, Chu W
J Imaging Inform Med
. 2024 Nov;
PMID: 39495442
Multiple instance learning (MIL) has become a cornerstone in whole slide image (WSI) analysis. In this paradigm, a WSI is conceptualized as a bag of instances. Instance features are extracted...
4.
Ge Y, Chen S, Wu B, Zhang Y, Wang J, He X, et al.
Alzheimers Dement
. 2024 Jul;
20(9):6243-6256.
PMID: 39023044
Introduction: Alzheimer's disease (AD) is a devastating neurological disease with complex genetic etiology. Yet most known loci have only identified from the late-onset type AD in populations of European ancestry....
5.
Cheng Y, Chen S, Zhang Y, Guo Y, Wu K, Huang Y, et al.
CNS Neurosci Ther
. 2024 Jul;
30(7):e14857.
PMID: 39014454
Aims: Apply established cerebrospinal fluid (CSF) and serum biomarkers and novel combined indicators based on the amyloid/tau/neurodegeneration (ATN) framework to improve diagnostic and prognostic power in patients with rapidly progressive...
6.
Guo Y, Chen S, You J, Huang S, Chen Y, Zhang Y, et al.
Nat Hum Behav
. 2024 Jul;
8(10):2047-2066.
PMID: 38987357
Recent expansion of proteomic coverage opens unparalleled avenues to unveil new biomarkers of Alzheimer's disease (AD). Among 6,361 cerebrospinal fluid (CSF) proteins analysed from the ADNI database, YWHAG performed best...
7.
Shi Q, Liu W, Liu F, Zeng Y, Chen S, Chen K, et al.
J Alzheimers Dis
. 2024 Jun;
100(1):77-85.
PMID: 38848185
Background: Rapidly progressive dementia (RPD), characterized by a rapid cognitive decline leading to dementia, comprises a diverse range of disorders. Despite advancements in diagnosis and treatment, research on RPD primarily...
8.
Deng Y, Wu B, Yang L, He X, Kang J, Liu W, et al.
Nat Hum Behav
. 2024 Apr;
8(6):1194-1208.
PMID: 38589703
While numerous genomic loci have been identified for neuropsychiatric conditions, the contribution of protein-coding variants has yet to be determined. Here we conducted a large-scale whole-exome-sequencing study to interrogate the...
9.
Guo Y, You J, Zhang Y, Liu W, Huang Y, Zhang Y, et al.
Nat Aging
. 2024 Feb;
4(2):247-260.
PMID: 38347190
The advent of proteomics offers an unprecedented opportunity to predict dementia onset. We examined this in data from 52,645 adults without dementia in the UK Biobank, with 1,417 incident cases...
10.
Chen K, Wang M, Wu J, Zuo C, Huang Y, Wang W, et al.
Alzheimers Dement
. 2024 Feb;
20(4):2516-2525.
PMID: 38329281
Introduction: The objective of this study is to investigate the incremental value of amyloid positron emission tomography (Aβ-PET) in a tertiary memory clinic setting in China. Methods: A total of...