Yu-Shuan Chen
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Explore the profile of Yu-Shuan Chen including associated specialties, affiliations and a list of published articles.
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17
Citations
264
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Recent Articles
1.
Ting H, Guo Y, Su H, Chen Y, Lin S, Harn H, et al.
Cell Death Discov
. 2025 Jan;
11(1):23.
PMID: 39863573
The neuromuscular junction (NMJ) is essential for transmitting signals from motor neurons (MNs) to skeletal muscles (SKMs), and its dysfunction can lead to severe motor disorders. However, our understanding of...
2.
Khine A, Chen P, Chen Y, Chu S, Chen Y, Huang H, et al.
Tzu Chi Med J
. 2025 Jan;
37(1):49-57.
PMID: 39850391
Objectives: The optimization of polyethylene glycol (PEG)-based extracellular vesicles (EVs) extraction from human follicular fluid (FF) and serum was investigated, and their functional analysis was confirmed. The PEG-based EV results...
3.
Chuang S, Chen K, Cheng Y, Chen Y, Lin S, Chou H, et al.
Int J Biol Macromol
. 2024 Sep;
280(Pt 3):135894.
PMID: 39322160
Glioblastoma multiforme (GBM) is an aggressive and common brain tumor. The blood-brain barrier prevents several treatments from reaching the tumor. This study proposes a Chemo-Immunotherapy synergy treatment chemically crosslinked hydrogel...
4.
Chen Y, Hong Z, Lin Y, Tsao E, Chen P, Liu C, et al.
Drug Deliv Transl Res
. 2023 Dec;
14(7):1940-1953.
PMID: 38161195
A patient-friendly and efficient treatment method for patients with spinocerebellar ataxia type 3 (SCA3) was provided through a nose-to-brain liposomal system. Initially, PGK1 was overexpressed in HEK 293-84Q-GFP diseased cells...
5.
Wu T, Huang C, Tsai H, Lin T, Chen P, Darge H, et al.
Biomater Adv
. 2023 Dec;
156:213722.
PMID: 38101076
Noninvasive lung drug delivery is critical for treating respiratory diseases. Pluronic-based copolymers have been used as multifunctional materials for medical and biological applications. However, the Pluronic F127-based hydrogel is rapidly...
6.
Chen Y, Harn H, Hong Z, Huang Y, Lin Y, Zheng H, et al.
Eur J Pharm Sci
. 2023 Oct;
191:106608.
PMID: 37832855
Exosome therapy is a novel trend in regeneration medicine. However, identifying a suitable biomarker that can associate the therapeutic efficacy of exosomes with SCA3/MJD is essential. In this study, parental...
7.
Mekonnen T, Darge H, Tsai H, Birhan Y, Hanurry E, Gebrie H, et al.
Colloids Surf B Biointerfaces
. 2022 Feb;
213:112391.
PMID: 35158218
Enhancement of drug efficacy is essential in cancer treatment. The immune stimulator ovalbumin (Ova)-coated citric acid (AC-)-stabilized iron oxide nanoparticles (AC-IO-Ova NPs) and enhanced permeability and retention (EPR)-based tumor targeted...
8.
Lin E, Chen Y, Li Y, Chen S, Lee C, Huang M, et al.
Int J Mol Sci
. 2020 Jun;
21(12).
PMID: 32575820
Although butylidenephthalide (BP) is an efficient anticancer drug, its poor bioavailability renders it ineffective for treating drug-resistant brain tumors. However, this problem is overcome through the use of noninvasive delivery...
9.
Chen Y, Hong Z, Lin S, Harn H
Int J Mol Sci
. 2020 May;
21(9).
PMID: 32357546
Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is a progressive motor disease with no broadly effective treatment. However, most current therapies are based on symptoms rather than the underlying disease mechanisms....
10.
Chen Y, Lin E, Chiou T, Harn H
Tzu Chi Med J
. 2020 Apr;
32(2):113-120.
PMID: 32269942
Exosomes, 60-200-nm extracellular vesicles secreted from cells, have been used as an active pharmaceutical ingredient or drug carrier in disease treatment. Human- and plant-derived exosomes are registered in clinical trials,...