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Yu-Hang Chen

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Articles 48
Citations 1036
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Recent Articles
1.
Chen J, Shen R, Zhu J, Wang Y, Fu L, Chen Y, et al.
Funct Integr Genomics . 2025 Mar; 25(1):56. PMID: 40053129
Nasopharyngeal carcinoma (NPC) recurrence, distant metastasis, and drug resistance remain significant obstacles in clinical prognosis. Cancer stemness is hypothesized to be a key contributor, though direct evidence is sparse. We...
2.
Lu X, Li D, Wang Y, Zhang G, Wen T, Lu Y, et al.
Nat Commun . 2025 Jan; 16(1):442. PMID: 39774710
The zinc-activated channel (ZAC) is an atypical mammalian cys-loop receptor (CLR) that is activated by zinc ions and protons, allowing cations to pass through. The molecular mechanism that ligands use...
3.
Wang Y, Chu T, Wang X, Fan Y, Cao L, Chen Y, et al.
Cell Signal . 2024 Sep; 124:111406. PMID: 39270916
Cystathionine β-synthase (CBS) occupies a key position as the initiating and rate-limiting enzyme in the sulfur transfer pathway and plays a vital role in health and disease. CBS is responsible...
4.
Chen Y, Ren C, Liao Y
Front Psychiatry . 2024 Sep; 15:1414332. PMID: 39220180
Background: Hospital-acquired pneumonia is one of the most important causes of recurrent illness, disease progression, and even death during hospitalization. Patients with schizophrenia have the special characteristics of their disease,...
5.
Cao L, Wang X, Chu T, Wang Y, Fan Y, Chen Y, et al.
Exp Cell Res . 2024 Aug; 442(2):114233. PMID: 39216662
Gasotransmitters are endogenous gaseous signaling molecules that can freely pass through cell membranes and transmit signals between cells, playing multiple roles in cell signal transduction. Due to extensive and ongoing...
6.
Chen Y, Ren C, Yu C
Front Psychiatry . 2024 Jul; 15:1435394. PMID: 39045549
Background: Research from observational studies has demonstrated a link between Alzheimer's disease (AD) and a higher risk of cardiovascular disease (CVD). Uncertainty surrounds the exact genetic cause of AD and...
7.
Huang K, Gui C, Xu Y, Li X, Zhao H, Cao J, et al.
Nat Commun . 2024 Jul; 15(1):6215. PMID: 39043664
Integrating genomics and histology for cancer prognosis demonstrates promise. Here, we develop a multi-classifier system integrating a lncRNA-based classifier, a deep learning whole-slide-image-based classifier, and a clinicopathological classifier to accurately...
8.
Qin L, Deng Y, Zhang X, Tang L, Zhang C, Xu S, et al.
Proc Natl Acad Sci U S A . 2024 Jul; 121(29):e2323040121. PMID: 38985761
Stomata in leaves regulate gas (carbon dioxide and water vapor) exchange and water transpiration between plants and the atmosphere. SLow Anion Channel 1 (SLAC1) mediates anion efflux from guard cells...
9.
Wang X, Zheng M, He H, Zhu H, Zhao Y, Chen Y, et al.
Crit Care Med . 2024 Jun; 52(10):1624-1632. PMID: 38832833
Objectives: This study aimed to systematically assess the methodological quality and key recommendations of the guidelines for the diagnosis and treatment of liver failure (LF), furnishing constructive insights for guideline...
10.
Zhang X, Tang L, Nie J, Zhang C, Han X, Li Q, et al.
Nat Plants . 2023 Oct; 9(11):1924-1936. PMID: 37884653
Salinity is one of the most severe abiotic stresses that adversely affect plant growth and agricultural productivity. The plant Na/H antiporter Salt Overly Sensitive 1 (SOS1) located in the plasma...