Yu-Guan Wen
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Explore the profile of Yu-Guan Wen including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
104
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Recent Articles
1.
He J, Shang D, Wang Z, Li X, Wen Y
Health Policy Open
. 2023 Jun;
3:100067.
PMID: 37383576
Background: In recent years, there has been a significant worldwide increase in the use of generic drugs. China has committed to a consistency evaluation of generic drugs, with the aim...
2.
Li X, Huang S, Xiao T, Wang X, Kong W, Liu S, et al.
Front Pharmacol
. 2022 Sep;
13:966622.
PMID: 36172189
Paroxetine is one of the most potent selective serotonin reuptake inhibitors (SSRIs) approved for treating depression, panic disorder, and obsessive-compulsive disorder. There is evidence linking genetic polymorphisms and nonlinear metabolism...
3.
Xiao T, Hu J, Liu S, Lu H, Li X, Kong W, et al.
J Clin Pharm Ther
. 2022 Sep;
47(11):1811-1819.
PMID: 36101489
What Is Known And Objective: Olanzapine is an atypical antipsychotic drug used for mental disorders. There are limited studies providing sufficient pharmacokinetic data, thus the variability of concentrations of olanzapine...
4.
Huang S, Li X, Wang Z, Lu H, Xiao T, Ni X, et al.
J Anal Methods Chem
. 2022 Apr;
2022:5914581.
PMID: 35433070
A high-performance liquid chromatographic method coupled with triple quadrupole mass spectrometry (LC-MS/MS) for the analysis of blonanserin and its active metabolite, -desethyl blonanserin, in rat plasma has been developed and...
5.
Zhou W, Jia L, Deng Q, Wen Y, Shang D, Ni X, et al.
Dig Liver Dis
. 2021 Mar;
53(11):1422-1427.
PMID: 33753003
Background: Low-dose amitriptyline (AMT) is an effective treatment for diarrhea-dominant irritable bowel syndrome (IBS-D). Its efficacy depends upon its serum concentration and the patient's CYP2C19 genotype. Aims: To identify the...
6.
Wang S, Ni X, Wen Y, Xie H, Chen J, Luo Y, et al.
J Pharm Biomed Anal
. 2020 Oct;
192:113657.
PMID: 33053506
Montelukast is a potent and selective antagonist of the cysteinyl leukotriene receptor 1 subtype (CysLT1) and widely used in the form of oral tablets and granules for asthma prophylaxis and...
7.
Wang Z, Deng S, Lu H, Li L, Zhu X, Hu J, et al.
Hum Psychopharmacol
. 2020 Apr;
35(3):e2733.
PMID: 32239743
Purpose: This study aimed to investigate the influence of diagnosis, body weight, sex, age, smoking, formulations, and concomitant drugs on steady-state dose-corrected serum concentrations (C/D) of venlafaxine (VEN) and O-desmethylvenlafaxine...
8.
Li L, Li L, Shang D, Wen Y, Ning Y
Br J Clin Pharmacol
. 2020 Feb;
86(4):668-678.
PMID: 32090363
Aims: Amisulpride, a first-line schizophrenia treatment, has shown large interindividual variability in plasma/serum levels, often outside the reference range (100-320 ng/mL). This study aims to clarify the impact of dose,...
9.
Deng S, Wang Z, Lu H, Li L, Hu J, Zhu X, et al.
Ther Drug Monit
. 2020 Feb;
42(4):636-642.
PMID: 32039940
Background: The objective of this study was to investigate the serum concentrations of olanzapine in relation to age, sex, and other factors in Chinese patients aged between 10 and 90...
10.
Wang Z, Zhang Y, Huang W, Wang X, Ni X, Lu H, et al.
Front Pharmacol
. 2019 Aug;
10:832.
PMID: 31404235
Lamotrigine (LTG) is a second-generation anti-epileptic drug widely used for focal and generalized seizures in adults and children, and as a first-line medication in pregnant women and women of childbearing...