Yu-Fu Wu
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Explore the profile of Yu-Fu Wu including associated specialties, affiliations and a list of published articles.
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11
Citations
95
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Recent Articles
1.
Wu Y, Chen J, Jong Y
J Biomed Sci
. 2025 Feb;
32(1):30.
PMID: 39985020
In this review, we highlight recent advancements in adeno-associated virus (AAV)-based gene therapy for genetic neuromuscular diseases (NMDs), focusing on spinal muscular atrophy (SMA) and Duchenne muscular dystrophy (DMD). We...
2.
Chen T, Chang S, Wu Y, Yen Y, Hsu F, Chen Y, et al.
Mol Ther Nucleic Acids
. 2023 Apr;
32:144-160.
PMID: 37064776
Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by the selective loss of spinal motor neurons (MNs) and concomitant muscle weakness. Mutation of is known to cause SMA, and...
3.
Wu Y, De La Toba E, Dvoretskiy S, Jung R, Kim N, Daniels L, et al.
J Physiol
. 2022 Mar;
601(22):5011-5031.
PMID: 35318675
Extended periods of bed rest and limb immobilization are required for healing post-injury or disease, yet disuse can result in significant muscle atrophy and decreased quality of life in older...
4.
Huang Y, Wu Y, Wang H, Yao C, Chiu Y, Sun J, et al.
Connect Tissue Res
. 2022 Mar;
63(6):590-602.
PMID: 35229695
Purpose: Mechanical stimuli are essential for the maintenance of tendon tissue homeostasis. The study aims to elucidate the mechanobiological mechanisms underlying the maintenance of tenocyte homeostasis by cyclic mechanical stretch...
5.
Wu Y, Lapp S, Dvoretskiy S, Garcia G, Kim M, Tannehill A, et al.
J Appl Physiol (1985)
. 2022 Feb;
132(4):1020-1030.
PMID: 35175105
Extended bed rest or limb immobilization can significantly reduce skeletal muscle mass and function. Recovery may be incomplete, particularly in older adults. Our laboratory recently reported that vascular mural cell...
6.
Mavropalias G, Wu Y, Boppart M, Blazevich A, Nosaka K
Med Sci Sports Exerc
. 2021 Sep;
54(1):89-97.
PMID: 34468415
Purpose: Recently, it has been suggested that a cellular pathway composed of integrin, integrin-linked kinase (ILK), rapamycin-insensitive companion of mTOR (RICTOR), and Akt may facilitate long-term structural and functional adaptations...
7.
Garg K, Mahmassani Z, Dvoretskiy S, Valero M, Huntsman H, Lapp S, et al.
J Gerontol A Biol Sci Med Sci
. 2020 Dec;
76(4):586-590.
PMID: 33284954
Anabolic resistance to a mechanical stimulus may contribute to the loss of skeletal muscle mass observed with age. In this study, young and aged mice were injected with saline or...
8.
Leong J, Hong Y, Wu Y, Ko E, Dvoretskiy S, Teo J, et al.
ACS Nano
. 2020 Apr;
14(5):5298-5313.
PMID: 32243129
Stem cell transplantation has been a promising treatment for peripheral arterial diseases in the past decade. Stem cells act as living bioreactors of paracrine factors that orchestrate tissue regeneration. Prestimulated...
9.
Mao Q, Liang X, Wu Y, Pang Y, Zhao X, Lu Y
Gene Ther
. 2019 Mar;
26(5):165-176.
PMID: 30814673
Mesenchymal stem cells (MSCs) have been applied in treating various diseases including myocardial infarction (MI) and achieved a bit of success; however, the decreased survival rate of MSCs after transplantation...
10.
Wu Y, Huang Y, Wang H, Yao C, Sun J, Chao Y
Int J Mol Sci
. 2017 Dec;
19(1).
PMID: 29283422
Diabetes mellitus is associated with damage to tendons, which may result from cellular dysfunction in response to a hyperglycemic environment. Tenocytes express diminished levels of tendon-associated genes under hyperglycemic conditions....