Yu-Chan Chih
Overview
Explore the profile of Yu-Chan Chih including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
45
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0
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Recent Articles
1.
Chih Y, Dietsch A, Koopmann P, Ma X, Agardy D, Zhao B, et al.
Nat Commun
. 2025 Feb;
16(1):1262.
PMID: 39893177
T cell receptor-engineered T cells (TCR-T) could be advantageous in glioblastoma by allowing safe and ubiquitous targeting of the glioblastoma-derived peptidome. Protein tyrosine phosphatase receptor type Z1 (PTPRZ1), is a...
2.
Kramer C, Kilian M, Chih Y, Kourtesakis A, Hoffmann D, Boschert T, et al.
Neuro Oncol
. 2023 Sep;
26(2):266-278.
PMID: 37715782
Background: Neuroligin 4 X-linked (NLGN4X) harbors a human leukocyte antigen (HLA)-A*02-restricted tumor-associated antigen, overexpressed in human gliomas, that was found to induce specific cytotoxic T cell responses following multi-peptide vaccination...
3.
Kilian M, Sheinin R, Tan C, Friedrich M, Kramer C, Kaminitz A, et al.
Cancer Cell
. 2023 Jan;
41(2):235-251.e9.
PMID: 36638785
Cancer immunotherapy critically depends on fitness of cytotoxic and helper T cell responses. Dysfunctional cytotoxic T cell states in the tumor microenvironment (TME) are a major cause of resistance to...
4.
Bunse L, Bunse T, Kramer C, Chih Y, Platten M
Neurotherapeutics
. 2022 Oct;
19(6):1799-1817.
PMID: 36303101
Gliomas are highly treatment refractory against immune checkpoint blockade, an immunotherapeutic modality that revolutionized therapy for many tumors. At the same time, technological innovation has dramatically accelerated the development of...
5.
Tu W, Chih Y, Shih Y, Yu Y, You L, Chen C
J Pathol
. 2022 Jul;
258(2):149-163.
PMID: 35781884
Diphthamide biosynthesis protein 1 (DPH1) is biochemically involved in the first step of diphthamide biosynthesis, a post-translational modification of eukaryotic elongation factor 2 (EEF2). Earlier studies showed that DPH1, also...