Youssef M Roman
Overview
Explore the profile of Youssef M Roman including associated specialties, affiliations and a list of published articles.
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23
Citations
116
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Recent Articles
1.
Ahmed M, Krishna R, Rayad N, Albusaysi S, Mitra A, Shang E, et al.
Clin Pharmacol Ther
. 2024 Aug;
116(6):1412-1432.
PMID: 39148459
In the relentless pursuit of optimizing drug development, the intricate process of determining the ideal dosage unfolds. This involves "dose-finding" studies, crucial for providing insights into subsequent registration trials. However,...
2.
Diallo A, Mackiewicz M, Sargent L, Roman Y, Slattum P, Waters L, et al.
Fam Community Health
. 2023 Oct;
47(1):32-40.
PMID: 37831622
Participation of Black American older adults in community-engaged research remains challenging in health sciences. The objectives of this study were to describe the specific efforts, successes, and challenges in recruiting...
3.
Roman Y
J Pers Med
. 2023 Sep;
13(9).
PMID: 37763176
Uric acid is the final product of purine metabolism and is converted to allantoin in most mammals via the uricase enzyme. The accumulation of loss of function mutations in the...
4.
Hang Y, Lee C, Roman Y
Biomark Med
. 2023 Jul;
17(8):445-454.
PMID: 37449859
Nonalcoholic fatty liver disease (NAFLD) is currently the most common form of chronic liver disease. The growing prevalence of NAFLD is strongly associated with the high incidence of metabolic syndrome....
5.
6.
Mitra A, Ahmed M, Krishna R, Sun K, Gibbons F, Campagne O, et al.
Clin Pharmacol Ther
. 2023 Jun;
114(3):515-529.
PMID: 37313953
The promise of viral vector-based gene therapy (GT) as a transformative paradigm for treating severely debilitating and life-threatening diseases is slowly coming to fruition with the recent approval of several...
7.
Vo V, Lopez G, Malay S, Roman Y
J Immigr Minor Health
. 2023 May;
26(2):409-420.
PMID: 37222869
The growing prevalence of cardiovascular diseases in the United States (US) has disproportionately affected minority populations more than their white counterparts. A population that is often overlooked is the Asian...
8.
Wen Y, Brundage R, Roman Y, Culhane-Pera K, Straka R
Br J Clin Pharmacol
. 2023 May;
89(10):2964-2976.
PMID: 37202871
Aims: The aim of this study was to quantify identifiable sources of variability, including key pharmacogenetic variants in oxypurinol pharmacokinetics and their pharmacodynamic effect on serum urate (SU). Methods: Hmong...
9.
AlAzzeh O, Roman Y
Pharmacogenomics
. 2023 Jan;
24(3):173-182.
PMID: 36661065
Statins are among the most commonly prescribed medications worldwide. Rosuvastatin is a moderate- to high-intensity statin depending on the prescribed dose. Statin-associated muscle symptoms are the main side effects, contributing...
10.
Alrajeh K, Roman Y
Pharmacogenomics
. 2023 Jan;
24(1):15-26.
PMID: 36651271
Statins are widely used medications for the primary and secondary prevention of cardiovascular diseases. Statin-induced musculoskeletal symptoms are the primary adverse drug events contributing to poor adherence to lipid-lowering therapy....