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Young Sun Oh

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Articles 16
Citations 559
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Recent Articles
1.
Jung S, Cheong S, Lee Y, Lee J, Lee J, Kwon M, et al.
ACS Nano . 2025 Jan; 19(2):2975. PMID: 39788923
No abstract available.
2.
Sung K, Han S, Lee J, Kwon M, Kim D, Oh Y
Anticancer Res . 2024 Oct; 44(11):5147-5155. PMID: 39477293
Background/aim: Lung cancer remains a leading cause of cancer-related mortality worldwide, necessitating the development of effective early diagnostic strategies. Despite advancements in imaging and screening technologies, late-stage diagnoses remain common,...
3.
Jung S, Cheong S, Lee Y, Lee J, Lee J, Kwon M, et al.
ACS Nano . 2024 Aug; 18(36):24909-24928. PMID: 39208278
This research introduces a vascular phenotypic and proteomic analysis (VPT) platform designed to perform high-throughput experiments on vascular development. The VPT platform utilizes an open-channel configuration that facilitates angiogenesis by...
4.
Keuls R, Oh Y, Patel I, Parchem R
Proc Natl Acad Sci U S A . 2023 Feb; 120(6):e2212578120. PMID: 36724256
Developmental potential is progressively restricted after germ layer specification during gastrulation. However, cranial neural crest cells challenge this paradigm, as they develop from anterior ectoderm, yet give rise to both...
5.
Jun S, Jung Y, Suh H, Wang W, Kim M, Oh Y, et al.
Nat Commun . 2016 Mar; 7:10994. PMID: 27009971
Despite the implication of Wnt signalling in radioresistance, the underlying mechanisms are unknown. Here we find that high Wnt signalling is associated with radioresistance in colorectal cancer (CRC) cells and...
6.
Wang X, Jung Y, Jun S, Lee S, Wang W, Schneider A, et al.
Nat Commun . 2016 Feb; 7:10633. PMID: 26843124
Cancer stem cells (CSCs) contribute to tumour heterogeneity, therapy resistance and metastasis. However, the regulatory mechanisms of cancer cell stemness remain elusive. Here we identify PCNA-associated factor (PAF) as a...
7.
Lee S, Yu K, Ryu Y, Oh Y, Hong I, Kim H, et al.
Age (Dordr) . 2014 Dec; 36(6):9724. PMID: 25465621
Previously, AIMP3 (aminoacyl-tRNAsynthetase-interacting multifunctional protein-3) was shown to be involved in the macromolecular tRNA synthetase complex or to act as a tumor suppressor. In this study, we report a novel...
8.
Lee J, Kim D, Kim B, Yang W, Hong J, Kang T, et al.
J Cell Sci . 2014 Aug; 127(Pt 19):4234-45. PMID: 25097229
Aminoacyl-tRNA synthetases (ARSs) acylate transfer (t)RNAs with amino acids. Charging tRNAs with the right amino acids is the first step in translation; therefore, the accurate and error-free functioning of ARSs...
9.
Jung S, Lee J, Park J, Oh Y, Lee S, Park J, et al.
Nat Commun . 2013 Oct; 4:2562. PMID: 24096742
Transforming growth factor (TGF)-β, a pivotal cytokine involved in a variety of cellular functions, transmits signals through Smad-dependent canonical and Smad-independent noncanonical pathways. In contrast to the canonical TGF-β pathway,...
10.
Lee H, Kim D, Oh Y, Kwon N, Lee J, Kim D, et al.
Biochem J . 2013 Jul; 454(3):411-6. PMID: 23815603
AIMP2 (aminoacyl-tRNA synthetase-interacting multifunctional protein 2) is a potent tumour suppressor that induces apoptosis in response to various oncogenic signals. AIMP2-DX2, an exon2-deleted splicing variant of AIMP2, is up-regulated in...