Young Mi Seok
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Explore the profile of Young Mi Seok including associated specialties, affiliations and a list of published articles.
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32
Citations
463
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Recent Articles
1.
Bai L, Kee H, Choi S, Seok Y, Kim G, Kee S, et al.
Biomed Pharmacother
. 2020 Dec;
134:111162.
PMID: 33360932
Non-specific histone deacetylase (HDAC) inhibition reduces high blood pressure in essential hypertensive animal models. However, the exact HDAC isoforms that play a critical role in controlling hypertension are not known....
2.
Seok Y, Yoo J, Nam Y, Kim J, Kim J, Son J, et al.
J Ethnopharmacol
. 2020 Nov;
270:113557.
PMID: 33161026
Ethnopharmacological Relevance: Mountain ginseng (Panax ginseng C.A. Meyer) is a medicinal herb with immune effects, muscle damage protection and energy metabolism effects. However, the pharmacological role of mountain ginseng in...
3.
Kim J, Yoo J, Kim J, Kim S, Park J, Seok Y, et al.
Evid Based Complement Alternat Med
. 2020 Aug;
2020:2584783.
PMID: 32774407
Mountain ginseng has been used generally as a pharmacopuncture for cancer therapy in clinical practice in Northeast Asia. Nonetheless, there have been few scientific reports for the anticancer action of...
4.
Kee H, Ryu Y, Seok Y, Choi S, Sun S, Kim G, et al.
Clin Hypertens
. 2019 Jun;
25:13.
PMID: 31223486
Background: The dysregulation of histone deacetylase (HDAC) protein expression or its enzyme activity is implicated in a variety of diseases. Cardiac HDAC6 and HDAC8 enzyme activity induced by deoxycorticosterone acetate...
5.
Ryu Y, Kee H, Sun S, Seok Y, Choi S, Kim G, et al.
PLoS One
. 2019 Mar;
14(3):e0213186.
PMID: 30830950
Objective: Non-selective histone deacetylase (HDAC) inhibitors are known to improve hypertension. Here, we investigated the therapeutic effect and regulatory mechanism of the class I HDAC selective inhibitors, MS-275 and RGFP966,...
6.
Choi S, Kee H, Sun S, Seok Y, Ryu Y, Kim G, et al.
J Cell Mol Med
. 2019 Feb;
23(4):2801-2812.
PMID: 30734467
Here, we report that LMK235, a class I and histone deacetylase (HDAC6)-preferential HDAC inhibitor, reduces hypertension via inhibition of vascular contraction and vessel hypertrophy. Angiotensin II-infusion mice and spontaneously hypertensive...
7.
Cho H, Seok Y, Lee H, Song M, Kim I
Int J Mol Sci
. 2018 Nov;
19(11).
PMID: 30424007
Methods: Male Long-Evans Tokushima Otsuka (LETO) and Otsuka Long-Evans Tokushima Fatty (OLETF) rats aged 14 weeks were administered sodium valproate (VPA, 0.71% /) dissolved in water for 20 weeks. Electrophoretic...
8.
Jin L, Piao Z, Sun S, Liu B, Kim G, Seok Y, et al.
Sci Rep
. 2017 Nov;
7(1):15607.
PMID: 29142252
Gallic acid (GA) has been reported to have beneficial effects on cancer, vascular calcification, and diabetes-induced myocardial dysfunction. We hypothesized that GA controls hypertension via oxidative stress response regulation in...
9.
Seok Y, Lee H, Park K, Hwangbo M, Kim I
Naunyn Schmiedebergs Arch Pharmacol
. 2016 Apr;
389(7):799-808.
PMID: 27106211
Inhibition of lysine deacetylase (KDAC) attenuated development of hypertension in spontaneously hypertensive rats (SHRs). We hypothesized that KDAC inhibition attenuates hypertension and is accompanied by acetylation of mineralocorticoid receptors (MR)...
10.
Seo M, Song M, Seok Y, Kang S, Lee H, Sohn U, et al.
Clin Exp Pharmacol Physiol
. 2015 Feb;
42(5):559-66.
PMID: 25707758
Acetylation of the mineralocorticoid receptor (MR) by inhibition of lysine deacetylases attenuates MR's transcriptional activity. However, the specific lysine acetyltransferases that are responsible for acetylation of the MR remain unknown....