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Young-Rae Lee

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Articles 92
Citations 1166
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Recent Articles
1.
Song H, Kim J, Noh E, Youn H, Lee Y
Mol Med Rep . 2024 Sep; 30(4). PMID: 39219290
NADPH oxidases (NOXs) are a family of membrane proteins responsible for intracellular reactive oxygen species (ROS) generation by facilitating electron transfer across biological membranes. Despite the established activation of NOXs...
2.
Jang H, Kim J, Kim J, Kim B, Lee Y, Bae J
Nutrients . 2023 Jul; 15(14). PMID: 37513611
(PB)-derived bioactive substances have been used as food and medicine in many Asian countries because of their antioxidant, antidiabetic, anti-cancer, and hepatoprotective properties. However, the effect of PB extracts (PBE)...
3.
Kim J, Noh E, You Y, Kim M, Lee Y
Biomed Res Int . 2022 Oct; 2022:3865844. PMID: 36246974
Matriptases are cell surface proteolytic enzymes belonging to the type II transmembrane serine protease family that mediate inflammatory skin disorders and cancer progression. Matriptases may affect the development of periodontitis...
4.
Hong O, Jang H, Lee Y, Jung S, Youn H, Kim J
Sci Rep . 2022 Jul; 12(1):12125. PMID: 35840633
Sirtuin 6 (SIRT6) regulation is involved in carcinogenesis. However, its role in breast cancer (BC) metastasis remains unclear. We investigated the effects of SIRT6 on protein kinase C activator- and...
5.
Kim J, Park J, Noh E, Song H, Kang S, Jung S, et al.
Oncol Rep . 2021 Oct; 46(6). PMID: 34608498
Matriptases, members of the type II transmembrane serine protease family, are cell surface proteolytic enzymes that mediate tumor invasion and metastasis. Matriptase is highly expressed in breast cancer and is...
6.
Song H, Noh E, Kim J, You Y, Kwon K, Lee Y
Evid Based Complement Alternat Med . 2021 Sep; 2021:5858393. PMID: 34504537
Periodontitis is a Gram-negative bacterial infectious disease. Numerous inflammatory cytokines, including interleukin-1 (IL-1), regulate periodontitis pathophysiology and cause periodontal tissue destruction. In human gingival fibroblasts (HGFs), IL-1 stimulates the production...
7.
Kim J, Park J, Noh E, Song H, Kang S, Jung S, et al.
Oncol Rep . 2021 Mar; 45(5). PMID: 33760219
Bruton's agammaglobulinemia tyrosine kinase (BTK) is an important cytoplasmic tyrosine kinase involved in B‑lymphocyte development, differentiation, and signaling. Activated protein kinase C (PKC), in turn, induces the activation of mitogen‑activated...
8.
Jang H, Lee H, Noh E, Kim J, You Y, Lee G, et al.
Arch Oral Biol . 2021 Jan; 122:105029. PMID: 33387850
Objective: The flower of chrysanthemum, used worldwide as a medicinal and edible product, has shown various bioactivities, such as anti-inflammatory, antioxidant, anti-tumorigenic, and hepatoprotective activities, as well as cardiovascular protection....
9.
Noh E, Kim J, Lee H, Song H, Joung S, Yang H, et al.
BMC Complement Altern Med . 2019 Nov; 19(1):322. PMID: 31752816
Background: Platycodon grandiflorum is a flowering plant that is used in traditional medicine for treating pulmonary and respiratory disorders. It exerts various pharmacological effects, including immunomodulatory and anti-cancer activities. The...
10.
Song H, Noh E, Kim J, You Y, Kwon K, Lee Y
Arch Oral Biol . 2019 Aug; 108:104530. PMID: 31470141
Objective: Periodontitis is an inflammatory disease of the supporting tissue around teeth commonly caused by gram-negative bacterial infections. Interleukin (IL)-1β, a cytokine involved in host immune and inflammatory responses, is...