You Kyung Cho
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Explore the profile of You Kyung Cho including associated specialties, affiliations and a list of published articles.
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5
Citations
95
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Recent Articles
1.
Eom S, Peak J, Park J, Ahn S, Cho Y, Jeong Y, et al.
Nat Cell Biol
. 2023 Sep;
25(9):1369-1383.
PMID: 37696949
Oxidative stress contributes to tumourigenesis by altering gene expression. One accompanying modification, 8-oxoguanine (oG) can change RNA-RNA interactions via oG•A base pairing, but its regulatory roles remain elusive. Here, on...
2.
Seo G, Lee H, Lee J, Han H, Cho Y, Kim M, et al.
Mol Med
. 2022 Mar;
28(1):38.
PMID: 35346031
Background: The diagnostic yield of whole-exome sequencing (WES) varies from 30%-50% among patients with mild to severe neurodevelopmental delay (NDD)/intellectual disability (ID). Routine retrospective reanalysis of undiagnosed patients has increased...
3.
Gu D, Ahn S, Eom S, Lee H, Ham J, Lee D, et al.
Mol Ther Nucleic Acids
. 2021 Mar;
23:1172-1190.
PMID: 33664996
Small interfering RNAs (siRNAs) therapeutically induce RNA interference (RNAi) of disease-causing genes, but they also silence hundreds of seed-matched off-targets as behaving similar to microRNAs (miRNAs). miRNAs control the pathophysiology...
4.
Seok H, Lee H, Lee S, Ahn S, Lee H, Kim G, et al.
Nature
. 2020 Aug;
584(7820):279-285.
PMID: 32760005
In pathophysiology, reactive oxygen species oxidize biomolecules that contribute to disease phenotypes. One such modification, 8-oxoguanine (oG), is abundant in RNA but its epitranscriptional role has not been investigated for...
5.
Park S, Ahn S, Cho E, Cho Y, Jang E, Chi S
Nucleic Acids Res
. 2018 Oct;
46(21):11153-11168.
PMID: 30329090
High-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP, also called CLIP-Seq) has been used to map global RNA-protein interactions. However, a critical caveat of HITS-CLIP results is that they...