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You-Qiang Su

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Articles 38
Citations 2198
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Recent Articles
1.
Li H, Zhao H, Yang C, Su R, Long M, Liu J, et al.
Adv Sci (Weinh) . 2023 Apr; 10(18):e2300043. PMID: 37083226
Mammalian oogenesis features reliance on the mRNAs produced and stored during early growth phase. These are essential for producing an oocyte competent to undergo meiotic maturation and embryogenesis later when...
2.
Wang Z, Wei H, Wu Z, Zhang X, Sun Y, Gao L, et al.
Commun Biol . 2022 Dec; 5(1):1327. PMID: 36463362
As the time of ovulation draws near, mouse spermatozoa move out of the isthmic reservoir, which is a prerequisite for fertilization. However, the molecular mechanism remains unclear. The present study...
3.
Su Y, Yin Y, Guo J, Gong X, Tian Y, Shi L
Biol Reprod . 2022 May; 107(1):76-84. PMID: 35552649
Coordinated development of the germline and the somatic compartments within a follicle is an essential prerequisite for creating a functionally normal oocyte. Bi-directional communication between the oocyte and the granulosa...
4.
Yin H, Hou X, Zhang T, Shi L, Su Y
J Biomed Res . 2022 Jan; 34(1):44-53. PMID: 35081682
The generation of a high-quality egg for reproduction requires faithful segregation of chromosome during oocyte meiosis. Here, we report that echinoderm microtubule-associated protein like 6 (EML6) is highly expressed in...
5.
Zhang H, Zhang F, Chen Q, Li M, Lv X, Xiao Y, et al.
Nat Cell Biol . 2021 Sep; 23(9):1013-1022. PMID: 34489574
Piwi-interacting RNAs (piRNAs) are predominantly expressed in germ cells and function in gametogenesis in various species. However, Piwi-deficient female mice are fertile and mouse oocytes express a panel of small...
6.
Chen X, Hu C, Fan X, Wang Y, Li Q, Su Y, et al.
Am J Respir Cell Mol Biol . 2021 Jul; 65(6):646-657. PMID: 34251297
Compromised endothelial-cell (EC) barrier function is a hallmark of inflammatory diseases. mTOR inhibitors, widely applied as clinical therapies, cause pneumonitis through mechanisms that are not yet fully understood. This study...
7.
Ni S, Zhang T, Zhou C, Long M, Hou X, You L, et al.
Front Cell Dev Biol . 2021 Jun; 9:690536. PMID: 34124077
Inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme catalyzing biosynthesis of guanine nucleotides, aggregates under certain circumstances into a type of non-membranous filamentous macrostructure termed "cytoophidium" or "rod and ring" in...
8.
Yin H, Zhang T, Wang H, Hu X, Hou X, Fang X, et al.
Front Cell Dev Biol . 2021 Jun; 9:687522. PMID: 34124073
Completion of the first meiosis is an essential prerequisite for producing a functionally normal egg for fertilization and embryogenesis, but the precise mechanisms governing oocyte meiotic progression remains largely unclear....
9.
Li H, You L, Tian Y, Guo J, Fang X, Zhou C, et al.
Adv Sci (Weinh) . 2020 Jul; 7(14):2000531. PMID: 32714760
Post-translational modification of proteins by -linked glycosylation is crucial for many life processes. However, the exact contribution of -glycosylation to mammalian female reproduction remains largely undefined. Here, DPAGT1, the enzyme...
10.
Xu P, Huang B, Zhan J, Liu M, Fu Y, Su Y, et al.
J Clin Endocrinol Metab . 2018 Nov; 104(7):2547-2560. PMID: 30476103
Context: Women with obesity usually need larger doses of FSH for ovarian stimulation, resulting in poor outcomes; however, the mechanism is still unclear. Objective: To investigate the molecular regulation of...