Yoshiki Takai
Overview
Explore the profile of Yoshiki Takai including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
67
Citations
1294
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Watanabe G, Takai Y, Nagane Y, Kubota T, Yasuda M, Akamine H, et al.
Front Immunol
. 2025 Jan;
15:1502721.
PMID: 39763650
International consensus guidance and Japanese clinical guidelines for myasthenia gravis (MG) recommend achieving minimal manifestations or better status (MM-or-better) as the severity component of the treatment goal. However, the subjective...
2.
Yamazaki N, Misu T, Matsumoto Y, Takai Y, Namatame C, Ono H, et al.
Mult Scler Relat Disord
. 2024 Nov;
92:106176.
PMID: 39579645
Background: Neuromyelitis optica spectrum disorder (NMOSD), a central nervous system inflammatory disease associated with aquaporin-4 immunoglobulin G (AQP4-IgG), is conventionally treated with oral steroids and immunosuppressants (IS) in Japan. Several...
3.
Kato D, Kameda H, Kinota N, Fujii T, Xiawei B, Simi Z, et al.
Sci Rep
. 2024 Nov;
14(1):27982.
PMID: 39543281
The aquaporin-4 (AQP4) water channel is essential in neurofluid dynamics. AQP4 loss impairs solute exchange between the cerebrospinal fluid (CSF) and interstitial fluid (ISF). However, whether AQP4 expression affects solute...
4.
Niino M, Isobe N, Araki M, Ohashi T, Okamoto T, Ogino M, et al.
Mult Scler Relat Disord
. 2024 Aug;
90:105829.
PMID: 39182455
Background: The previous Japanese clinical practice guidelines for multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) were published in 2017. Recently, for the first time in 6 years, the...
5.
Kaneko K, Kuroda H, Matsumoto Y, Sakamoto N, Yamazaki N, Yamamoto N, et al.
Neurol Neuroimmunol Neuroinflamm
. 2024 Aug;
11(5):e200293.
PMID: 39133885
Objectives: In myelin oligodendrocyte glycoprotein IgG-associated disease (MOGAD) and aquaporin-4 IgG+ neuromyelitis optica spectrum disorder (AQP4+NMOSD), the autoantibodies are mainly composed of IgG1, and complement-dependent cytotoxicity is a primary pathomechanism...
6.
Namatame C, Abe Y, Miyasaka Y, Takai Y, Matsumoto Y, Takahashi T, et al.
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125739
Conventional rodent neuromyelitis optica spectrum disorder (NMOSD) models using patient-derived immunoglobulin G (IgG) are potentially affected by the differences between the human and rodent aquaporin-4 (AQP4) extracellular domains (ECDs). We...
7.
Matsumoto Y, Tarasawa K, Misu T, Namatame C, Takai Y, Kuroda H, et al.
Mult Scler Relat Disord
. 2023 Dec;
81:105349.
PMID: 38043366
Background: The real-world data evidences how establishment of neuromyelitis optica (NMO) disease concept and development disease modifying therapy affect the patients with multiple sclerosis (MS) and NMO are lacking. The...
8.
Takai Y, Misu T, Fujihara K, Aoki M
Front Neurol
. 2023 Aug;
14:1209749.
PMID: 37545724
Myelin oligodendrocyte glycoprotein (MOG) is expressed on the outermost layer of the myelin sheath in the central nervous system. Recently, the clinical concept of MOG antibody-associated disease (MOGAD) was established...
9.
Akaishi T, Misu T, Fujihara K, Nakaya K, Nakaya N, Nakamura T, et al.
Sci Rep
. 2023 Apr;
13(1):6481.
PMID: 37081126
White blood cell (WBC) count profiles in anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD) and anti-myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are still unknown. This study evaluated the total WBC...
10.
Matsumoto Y, Kaneko K, Takahashi T, Takai Y, Namatame C, Kuroda H, et al.
Brain
. 2023 Apr;
146(9):3938-3948.
PMID: 37061817
The spectrum of MOG-IgG-associated disease (MOGAD) includes optic neuritis (ON), myelitis (MY), acute disseminated encephalomyelitis (ADEM), brainstem encephalitis, cerebral cortical encephalitis (CE) and AQP4-IgG-negative neuromyelitis optica spectrum disorder (NMOSD). In...