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Yoshihiro Osawa

Explore the profile of Yoshihiro Osawa including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 33
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Recent Articles
1.
Nomura K, Kimira Y, Kobayashi R, Shiobara Y, Osawa Y, Kataoka-Matsushita A, et al.
Front Nutr . 2024 May; 11:1375532. PMID: 38812940
Background: The global obesity epidemic is a significant public health issue, often leading to metabolic disorders such as diabetes and cardiovascular diseases. Collagen peptides (CP) and their bioactive component, Prolyl-hydroxyproline...
2.
Kimira Y, Osawa K, Osawa Y, Mano H
Biomolecules . 2023 Nov; 13(11). PMID: 38002299
Glucocorticoids, commonly used to manage inflammatory diseases, can induce muscle atrophy by accelerating the breakdown of muscle proteins. This research delves into the influence of Prolyl-hydroxyproline (Pro-Hyp), a collagen-derived peptide,...
3.
Kimira Y, Sato T, Sakamoto M, Osawa Y, Mano H
Molecules . 2023 Jun; 28(12). PMID: 37375217
Chondrocytes are surrounded by a lower oxygen environment than other well-vascularized tissues with higher oxygenation levels. Prolyl-hydroxyproline (Pro-Hyp), one of the final collagen-derived peptides, has been previously reported to be...
4.
Natsume T, Inaba Y, Osawa Y, Fukuyama T
Neuropediatrics . 2022 Jan; 53(4):239-245. PMID: 35098496
Background: Congenital cytomegalovirus (CMV) infection exhibits polymicrogyria, intracranial calcification, white matter lesions, and several types of intracranial lesions on magnetic resonance imaging (MRI), in addition to various developmental disorders and...
5.
Nomura K, Kimira Y, Osawa Y, Kataoka-Matsushita A, Takao K, Sugita Y, et al.
Biosci Rep . 2021 Nov; 41(12). PMID: 34779485
Collagen-derived dipeptide prolyl-hydroxyproline (Pro-Hyp) directly binds to the forkhead box g1 (Foxg1) protein and causes it to undergo structural alteration. Pro-Hyp also promotes the production of a regulator of osteoblast...
6.
Saito M, Ogasawara M, Inaba Y, Osawa Y, Nishioka M, Yamauchi S, et al.
Brain Dev . 2021 Sep; 44(1):50-55. PMID: 34565654
Background: Congenital myasthenic syndrome (CMS) is a clinically and genetically heterogeneous neuromuscular disorder characterized by muscle weakness and caused by mutations in more than 35 different genes. This condition should...
7.
Osawa Y, Nomura K, Kimira Y, Kushibe S, Takeyama K, Nagao M, et al.
Sci Rep . 2021 Jun; 11(1):13527. PMID: 34188133
Active collagen oligopeptides (ACOP) are bioactive collagen-derived peptides detected by a recently-established ELISA. To facilitate studies of the function and metabolism of these products, this study aims to determine which...
8.
Nomura K, Kimira Y, Osawa Y, Shimizu J, Kataoka-Matsushita A, Mano H
Biosci Biotechnol Biochem . 2019 Jul; 83(11):2027-2033. PMID: 31322484
Collagen-derived dipeptide prolyl hydroxyproline (Pro-Hyp) is involved in the proliferation and differentiation of various types of cultured cells. To elucidate the mechanism underlying Pro-Hyp actions during osteoblast differentiation, we hypothesized...
9.
Osawa Y, Mizushige T, Jinno S, Sugihara F, Inoue N, Tanaka H, et al.
Biomed Res . 2018 Feb; 39(1):1-11. PMID: 29467346
A number of studies have shown that oral administration of collagen hydrolysate (CH) results in the absorption of di- and tri-peptides. In order to understand the dynamics of CH absorption...
10.
Sueishi Y, Fujita T, Nakatani S, Inazumi N, Osawa Y
Spectrochim Acta A Mol Biomol Spectrosc . 2013 Jun; 114:344-9. PMID: 23786974
The association constants (K) for the inclusion complexation of four kinds of cyclodextrins (CDs (β- and γ-), 2,6-di-O-methylated β-CD, and 2,3,6-tri-O-methylated β-CD) and cucurbit[7]uril (CB[7]) with 1,8- and 2,6-anilinonaphthalene sulfonic...