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Yoshihiro Aiba

Explore the profile of Yoshihiro Aiba including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 598
Followers 0
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Recent Articles
1.
Hitomi Y, Ueno K, Aiba Y, Nishida N, Kono M, Sugihara M, et al.
Hepatology . 2024 Apr; 80(4):776-790. PMID: 38652555
Background And Aims: Previous genome-wide association studies (GWAS) have indicated the involvement of shared (population-nonspecific) and nonshared (population-specific) susceptibility genes in the pathogenesis of primary biliary cholangitis (PBC) among European...
2.
Hitomi Y, Ueno K, Aiba Y, Nishida N, Kawai Y, Kawashima M, et al.
Hum Genet . 2023 Nov; 143(1):19-33. PMID: 37994973
CD58 plays roles in cell adhesion and co-stimulation with antigen presentation from major histocompatibility complex class II on antigen-presenting cells to T-cell antigen receptors on naïve T cells. CD58 reportedly...
3.
Khor S, Ueno K, Nishida N, Kawashima M, Kawai Y, Aiba Y, et al.
Front Immunol . 2023 Jun; 14:1151502. PMID: 37325616
Primary biliary cholangitis (PBC) is a rare autoimmune disease with a clear predisposition for human leukocyte antigen -associated loss of immune tolerance for the E2 component of the pyruvate dehydrogenase...
4.
Cordell H, Fryett J, Ueno K, Darlay R, Aiba Y, Hitomi Y, et al.
J Hepatol . 2023 Jan; 78(4):883. PMID: 36639314
No abstract available.
5.
Hitomi Y, Aiba Y, Ueno K, Nishida N, Kawai Y, Kawashima M, et al.
Hum Genomics . 2022 Oct; 16(1):46. PMID: 36271469
Background: Ligation of CD28 with ligands such as CD80 or CD86 provides a critical second signal alongside antigen presentation by class II major histocompatibility complex expressed on antigen-presenting cells through...
6.
Cordell H, Fryett J, Ueno K, Darlay R, Aiba Y, Hitomi Y, et al.
J Hepatol . 2021 Dec; 76(2):489. PMID: 34895949
No abstract available.
7.
Hitomi Y, Aiba Y, Ueno K, Nishida N, Kawai Y, Kawashima M, et al.
J Autoimmun . 2021 Dec; 126:102775. PMID: 34864633
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease that appears to be strongly influenced by genetic factors. Recently, an international meta-analysis of genome-wide association studies (GWAS) identified...
8.
Cordell H, Fryett J, Ueno K, Darlay R, Aiba Y, Hitomi Y, et al.
J Hepatol . 2021 May; 75(3):572-581. PMID: 34033851
Backgrounds & Aims: Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intrahepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate...
9.
Gervais O, Ueno K, Kawai Y, Hitomi Y, Aiba Y, Ueta M, et al.
Eur J Hum Genet . 2021 Apr; 29(8):1282-1291. PMID: 33833419
While the advent of GWAS more than a decade ago has ushered in remarkable advances in our understanding of complex traits, the limitations of single-SNP analysis have also led to...
10.
Hitomi Y, Aiba Y, Kawai Y, Kojima K, Ueno K, Nishida N, et al.
Sci Rep . 2021 Feb; 11(1):4557. PMID: 33633225
Primary biliary cholangitis (PBC) is a chronic, progressive cholestatic liver disease in which intrahepatic bile ducts are destroyed by an autoimmune reaction. Our previous genome-wide association study (GWAS) identified chromosome...