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Yongzhen Xia

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Articles 55
Citations 662
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Recent Articles
1.
Xin Y, Wang Q, Yang J, Wu X, Xia Y, Xun L, et al.
Appl Environ Microbiol . 2025 Feb; :e0192624. PMID: 39918318
Polysulfides commonly occur in anaerobic, microbial active environments, where they play key roles in sulfur cycling and redox transformations. Anaerobic survival of microorganisms requires the formation of protein disulfide bond...
2.
Liu M, Ge W, Zhong G, Yang Y, Xun L, Xia Y
ACS Synth Biol . 2024 Oct; 13(11):3523-3538. PMID: 39418641
The efficiency of valuable metabolite production by engineered microorganisms underscores the importance of stable and controllable gene expression. While plasmid-based methods offer flexibility, integrating genes into host chromosomes can establish...
3.
Xia Y, Chen H, Qin J, Zhang W, Gao H, Long X, et al.
Phytomedicine . 2024 Aug; 133:155925. PMID: 39173278
Background: Nur77, an orphan member of the nuclear receptor superfamily, regulates inflammatory diseases and is a therapeutic target for treating inflammation. Phthalides in Angelica sinensis exhibit anti-inflammatory activity. Purpose: This...
4.
Xuan G, Xun L, Xia Y
mLife . 2024 Jul; 3(2):231-239. PMID: 38948149
Members of the multiple antibiotic resistance regulator (MarR) protein family are ubiquitous in bacteria and play critical roles in regulating cellular metabolism and antibiotic resistance. MarR family proteins function as...
5.
Wang Q, Zhang X, Du Z, Liu H, Xia Y, Xun L, et al.
Antioxidants (Basel) . 2024 May; 13(5). PMID: 38790694
YCA1, the only metacaspase in , plays important roles in the regulation of chronological lifespan, apoptosis, and cytokinesis. YCA1 has protein hydrolase activity and functions by cleaving itself and target...
6.
Chen X, Gao M, Xia Y, Wang X, Qin J, He H, et al.
Acta Pharm Sin B . 2024 Mar; 14(3):1204-1221. PMID: 38486987
The orphan nuclear receptor Nur77 is a critical regulator of the survival and death of tumor cells. The pro-death effect of Nur77 can be regulated by its interaction with Bcl-2,...
7.
Wu X, Wan J, Wang Q, Liu Z, Xia Y, Xun L, et al.
J Environ Manage . 2024 Feb; 354:120416. PMID: 38408391
Hydrogen sulfide (HS) is a toxic gas massively released during chicken manure composting. Diminishing its release requires efficient and low cost methods. In recent years, heterotrophic bacteria capable of rapid...
8.
Cao Q, Liu X, Wang Q, Liu Z, Xia Y, Xun L, et al.
mBio . 2024 Feb; 15(3):e0290723. PMID: 38329332
Importance: This study overthrows a long-time assumption that methanethiol oxidases (MTOs) cleave the C-S bond of methanethiol to produce both HS and HO-the former is a strong reductant and the...
9.
Wang T, Li X, Liu H, Liu H, Xia Y, Xun L
Sci Total Environ . 2024 Feb; 922:170504. PMID: 38307292
Zero-valent sulfur, commonly utilized as a fertilizer or fungicide, is prevalent in various environmental contexts. Its most stable and predominant form, octasulfur (S), plays a crucial role in microbial sulfur...
10.
Liu H, Yu H, Gao R, Ge F, Zhao R, Lu X, et al.
Antioxidants (Basel) . 2024 Jan; 13(1). PMID: 38247452
Podophyllotoxin (PTOX) is naturally produced by the plant Podophyllum species. Some of its derivatives are anticancer drugs, which are produced mainly by using chemical semi-synthesis methods. Recombinant bacteria have great...