Yongping Chai
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Explore the profile of Yongping Chai including associated specialties, affiliations and a list of published articles.
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36
Citations
498
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Recent Articles
1.
Xu K, Li Z, Mao L, Guo Z, Chen Z, Chai Y, et al.
PLoS Biol
. 2024 Aug;
22(8):e3002615.
PMID: 39159282
Dynamic properties are essential for microtubule (MT) physiology. Current techniques for in vivo imaging of MTs present intrinsic limitations in elucidating the isotype-specific nuances of tubulins, which contribute to their...
2.
Xie Z, Chai Y, Zhu Z, Shen Z, Guo Z, Zhao Z, et al.
Elife
. 2024 Jul;
12.
PMID: 38994733
Asymmetric cell divisions (ACDs) generate two daughter cells with identical genetic information but distinct cell fates through epigenetic mechanisms. However, the process of partitioning different epigenetic information into daughter cells...
3.
Chai Y, Li D, Gong W, Ke J, Tian D, Chen Z, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(5):e2311936121.
PMID: 38271337
KIF1A, a microtubule-based motor protein responsible for axonal transport, is linked to a group of neurological disorders known as KIF1A-associated neurological disorder (KAND). Current therapeutic options for KAND are limited....
4.
Shi B, Qin P, Li W, Feng H, Zhou Y, Chai Y, et al.
Inorg Chem
. 2023 Oct;
62(42):17236-17240.
PMID: 37816176
Considerable progress in the construction of efficient fluorescence-resonance energy transfer (FRET) systems has promoted the development of artificial energy transfer materials. However, despite recent advances, the exploration of efficient and...
5.
Shi B, Li X, Chai Y, Qin P, Zhou Y, Qu W, et al.
Angew Chem Int Ed Engl
. 2023 Jun;
62(31):e202305767.
PMID: 37280162
Macrocyclic molecule-based host-guest systems, which provide contributions for the design and construction of functional supramolecular structures, have gained increasing attention in recent years. In particular, platinum(II) metallacycle-based host-guest systems provide...
6.
Li D, Huang S, Chai Y, Zhao R, Gong J, Zhang Q, et al.
Sci China Life Sci
. 2023 May;
66(10):2342-2353.
PMID: 37160652
Sperm contributes essential paternal factors, including the paternal genome, centrosome, and oocyte-activation signals, to sexual reproduction. However, it remains unresolved how sperm contributes its RNA molecules to regulate early embryonic...
7.
Qu W, Liu T, Chai Y, Ji D, Che Y, Hu J, et al.
Org Biomol Chem
. 2023 May;
21(19):4022-4027.
PMID: 37128802
Amino acids play an important role in the formation of proteins, enzymes, hormones and peptides in animals. Moreover, aspartic acid and glutamic acid have a critical impact on the central...
8.
Jiang X, Shao W, Chai Y, Huang J, Mohamed M, Okten Z, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(34):e2207134119.
PMID: 35969738
Cilia are microtubule-based organelles that power cell motility and regulate sensation and signaling, and abnormal ciliary structure and function cause various ciliopathies. Cilium formation and maintenance requires intraflagellar transport (IFT),...
9.
Wu D, Huang J, Zhu H, Chen Z, Chai Y, Ke J, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(31):e2201096119.
PMID: 35895683
Cilium formation and regeneration requires new protein synthesis, but the underlying cytosolic translational reprogramming remains largely unknown. Using ribosome footprinting, we performed global translatome profiling during cilia regeneration in and...
10.
Zhu H, Li M, Zhao R, Li M, Chai Y, Zhu Z, et al.
Proc Natl Acad Sci U S A
. 2022 Jun;
119(24):e2122249119.
PMID: 35666862
Microvilli are actin-bundle-supported membrane protrusions essential for absorption, secretion, and sensation. Microvilli defects cause gastrointestinal disorders; however, mechanisms controlling microvilli formation and organization remain unresolved. Here, we study microvilli by...