Yongling Zhu
Overview
Explore the profile of Yongling Zhu including associated specialties, affiliations and a list of published articles.
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25
Citations
744
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Recent Articles
1.
Jo A, Deniz S, Cherian S, Xu J, Futagi D, DeVries S, et al.
Nat Commun
. 2023 Nov;
14(1):7746.
PMID: 38008788
Neural computations arise from highly precise connections between specific types of neurons. Retinal ganglion cells (RGCs) with similar stratification patterns are positioned to receive similar inputs but often display different...
2.
Jo A, Deniz S, Xu J, Duvoisin R, DeVries S, Zhu Y
Nat Commun
. 2023 Sep;
14(1):5937.
PMID: 37741839
A fundamental organizing plan of the retina is that visual information is divided into ON and OFF streams that are processed in separate layers. This functional dichotomy originates in the...
3.
Xu J, Contractor A, Zhu Y
STAR Protoc
. 2023 Jan;
3(4):101907.
PMID: 36595933
Although it is now known that certain neurons can produce, store, and release multiple neurotransmitters, their locations, abundance, and functions remain elusive. We developed intersectional genetic strategies to identify multi-transmitter...
4.
Xu J, Jo A, DeVries R, Deniz S, Cherian S, Sunmola I, et al.
Cell Rep
. 2022 Jul;
40(1):111036.
PMID: 35793636
Recent developments in intersectional strategies have greatly advanced our ability to precisely target brain cell types based on unique co-expression patterns. To accelerate the application of intersectional genetics, we perform...
5.
Genc B, Jara J, Sanchez S, Lagrimas A, Gozutok O, Kocak N, et al.
Gene Ther
. 2021 Dec;
29(3-4):178-192.
PMID: 34853443
There are no effective cures for upper motor neuron (UMN) diseases, such as amyotrophic lateral sclerosis (ALS), primary lateral sclerosis, and hereditary spastic paraplegia. Here, we show UMN loss occurs...
6.
Xu J, Marshall J, Kraniotis S, Nomura T, Zhu Y, Contractor A
Behav Brain Res
. 2021 May;
411:113378.
PMID: 34029630
Autism is a neurodevelopmental disorder characterized by impaired social interactions and restricted and repetitive behaviors. Although group 1 metabotropic glutamate receptors (mGluRs), and in particular mGluR5, have been extensively proposed...
7.
Xu J, DeVries S, Zhu Y
Hum Gene Ther
. 2020 May;
31(19-20):1086-1099.
PMID: 32368927
Adeno-associated virus (AAV) is the most commonly used viral vector for both biological and gene therapeutic applications. Although many methods have been developed to measure quantity attributes of AAV, they...
8.
Jo A, Xu J, Deniz S, Cherian S, DeVries S, Zhu Y
Front Neural Circuits
. 2018 Sep;
12:66.
PMID: 30186122
The mammalian retina harbors over 100 different cell types. To understand how retinal circuits work, it is essential to systematically access each type. A widely used approach for achieving targeted...
9.
Xu J, Zhu Y
BMC Biotechnol
. 2018 Sep;
18(1):52.
PMID: 30170595
Background: The LoxP site based genetic switch, the FLEX, also known as DIO (Double-Floxed Inverted Open reading frame), was invented to turn on gene expression via Cre-mediated recombination. Since its...
10.
Xu J, Marshall J, Fernandes H, Nomura T, Copits B, Procissi D, et al.
Cell Rep
. 2017 Feb;
18(8):1848-1857.
PMID: 28228252
Kainate receptors are members of the glutamate receptor family that regulate synaptic function in the brain. They modulate synaptic transmission and the excitability of neurons; however, their contributions to neural...