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Yongjian Chen

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Articles 127
Citations 1636
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Recent Articles
1.
Ou Q, Xie W, Yu Y, Ou B, Luo M, Chen Y, et al.
MedComm (2020) . 2025 Feb; 6(3):e70106. PMID: 39968495
Bladder cancer's high mortality underscores the need for precise staging, especially to differentiate between nonmuscle invasive bladder cancer (NMIBC) and muscle invasive bladder cancer (MIBC) types. This prospective study evaluated...
2.
Ruan P, Guo H, Yi P, Chen Y, Jia C, Yang M, et al.
Chem Biodivers . 2025 Feb; :e202402522. PMID: 39953920
Dysregulated activation of the interleukin-21 (IL-21)/IL-21 receptor (IL-21R) signaling pathway is strongly associated with inflammatory and autoimmune disorders, which positions the pathway as a promising therapeutic target. Given the current...
3.
Li J, Chen Y, Li S, Lyu G, Yan F, Guo J, et al.
Front Nutr . 2025 Jan; 11():1437373. PMID: 39839297
Background: Hyperuricemia and non-alcoholic fatty pancreas disease (NAFPD) are prevalent metabolic diseases, but the relationship between them remains underexplored. Methods: Eighteen Sprague-Dawley rats were randomly assigned to three groups: normal...
4.
Liu Z, Bian X, Luo L, Bjorklund A, Li L, Zhang L, et al.
Cell Stem Cell . 2024 Dec; 32(3):479-498.e8. PMID: 39729995
Wound healing is vital for human health, yet the details of cellular dynamics and coordination in human wound repair remain largely unexplored. To address this, we conducted single-cell multi-omics analyses...
5.
Zhao J, Yu Y, Ren W, Ding L, Chen Y, Yuan P, et al.
MedComm (2020) . 2024 Dec; 6(1):e70031. PMID: 39712455
This multicenter, single-arm, phase II clinical trial (NCT04034589) evaluated the efficacy and safety of pyrotinib combined with fulvestrant in patients with HR-positive/HER2-positive metastatic breast cancer who had experienced trastuzumab treatment...
6.
Zhang L, Chen X, Zhou B, Meng W, Zeng H, Chen Y, et al.
Acta Biomater . 2024 Dec; 193:316-333. PMID: 39701339
Immunotherapy has emerged as a highly promising strategy in the realm of cancer treatment, wherein immunogenic cell death (ICD) is considered a potential trigger for anti-tumor immunity by inducing adaptive...
7.
Yu Y, Cai G, Lin R, Wang Z, Chen Y, Tan Y, et al.
MedComm (2020) . 2024 Dec; 5(12):e70023. PMID: 39669975
Breast cancer is the leading cancer among women, with a significant number experiencing recurrence and metastasis, thereby reducing survival rates. This study focuses on the role of long noncoding RNAs...
8.
Chen H, Chen Y, Du B, Wang Z, Pan S, Zhang M, et al.
Plant Physiol Biochem . 2024 Dec; 219:109364. PMID: 39662389
Straw return to the field is an important measure for increasing soil fertility to increase production. Recent studies have shown that straw return to fields can increase rice yield, but...
9.
Yue S, Chen Y, Cui W, Lu X, Shen Y, Zhou F, et al.
Clin Chim Acta . 2024 Nov; 566:120031. PMID: 39547554
Objective: This study aimed to investigate the application potential of the abnormal glycan structure Siaα-2,6Gal in the early and differential diagnosis of lung cancer. Methods: Clinical data and serum samples...
10.
Chen Y, Wang Z, Huang Q, Wang Y, Yan F, Xiang S, et al.
Mol Biol Rep . 2024 Nov; 51(1):1126. PMID: 39505756
Background: Adamantinomatous craniopharyngiomas (ACPs), commonly seen in pediatrics and adults often present with large cystic cavities that can compress surrounding tissues, causing severe visual and endocrine symptoms. Complete resection of...