Yong-Yuan Zhang
Overview
Explore the profile of Yong-Yuan Zhang including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
289
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0
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Recent Articles
11.
Yuan G, Hu C, Zhou Y, Liu J, Huang H, Li Y, et al.
Br J Clin Pharmacol
. 2017 May;
83(10):2259-2265.
PMID: 28511283
Aims: Little clinical data are available regarding re-establishing the effective inhibition of entecavir (ETV)-resistant mutants. In this retrospective study, we aimed to compare the efficacies of four treatment regimens as...
12.
Zhang Y
PLoS One
. 2015 Dec;
10(12):e0145465.
PMID: 26713436
Previous mutation based studies showed that ablating synthesis of viral envelope proteins led to elevated hepadnaviral covalently closed circular DNA (cccDNA) amplification, but it remains unknown how cccDNA amplification is...
13.
Zhang Y, Hu K
J Med Virol
. 2015 May;
87(12):1989-99.
PMID: 25989114
Chronic hepatitis B virus (HBV) infection affects approximately 375 million people worldwide. Current antiviral treatment effectively controls, but rarely clears chronic HBV infection. In addition, a significant portion of chronic...
14.
Zhang Y, Hu K, Duan Z
Front Med
. 2014 May;
8(2):129-34.
PMID: 24871442
Chronic hepatitis B virus (HBV) infection is a significant threat to public health and an enormous burden on society. Mechanisms responsible for chronic HBV infection remain poorly understood. A better...
15.
Li Q, Zhang Y, Chiu S, Hu Z, Lan K, Cha H, et al.
PLoS Pathog
. 2014 May;
10(5):e1004163.
PMID: 24852294
Recent functional genomics studies including genome-wide small interfering RNA (siRNA) screens demonstrated that hepatitis C virus (HCV) exploits an extensive network of host factors for productive infection and propagation. How...
16.
17.
Zhang Y, Zhang B, Ishii K, Liang T
J Virol
. 2010 Jan;
84(7):3396-407.
PMID: 20089661
The mechanisms of hepatitis C virus (HCV) replication remain poorly understood, and the cellular factors required for HCV replication are yet to be completely defined. CD81 is known to mediate...
18.
Matsumura T, Hu Z, Kato T, Dreux M, Zhang Y, Imamura M, et al.
Gastroenterology
. 2009 Apr;
137(2):673-81.
PMID: 19394333
Background & Aims: Hepatitis C virus (HCV) gains entry into susceptible cells by interacting with cell surface receptor(s). Viral entry is an attractive target for antiviral development because of the...
19.
Zhang Y, Theele D, Summers J
J Virol
. 2005 Jul;
79(15):9896-903.
PMID: 16014950
Inoculation of 3-day-old (3D) or 3-week-old (3W) ducklings with duck hepatitis B virus results in chronic or transient infection, respectively. We previously showed that rapid production of neutralizing antibody following...
20.
Zhang Y, Summers J
J Virol
. 2004 Jan;
78(3):1195-201.
PMID: 14722274
Hepatitis B virus (HBV) frequently causes transient infections in adults but chronic infections in infants. The basis of these age-related outcomes is not known. Infection of ducks with duck hepatitis...