Yong-Wook Baek
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Explore the profile of Yong-Wook Baek including associated specialties, affiliations and a list of published articles.
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20
Citations
177
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Recent Articles
1.
Lee G, Lee S, Baek Y, Lim J, Chung K, Jeong H
Ecotoxicol Environ Saf
. 2025 Feb;
292:117930.
PMID: 39986058
Inhalation exposure to polyhexamethylene guanidine phosphate (PHMG-p), a primary component of humidifier disinfectants, has been linked to interstitial lung disease and potential carcinogenic effects. This study aimed to investigate epithelial...
2.
Lee H, Jeong S, Baek Y, Lee H, Sa J, Lee J, et al.
Chemosphere
. 2024 Dec;
370():144045.
PMID: 39741076
No abstract available.
3.
Seok J, Jee J, Jeon M, Kim D, Chung K, Kim H, et al.
J Toxicol Environ Health A
. 2024 Nov;
88(4):162-174.
PMID: 39604835
Polyhexamethyleneguanidine phosphate (PHMG), a widely used antimicrobial agent, has been implicated in humidifier disinfectant-associated lung injuries (HDLI). PHMG exposure suppressed interferon regulatory factor 3 (IRF3) activation and interferon-β (IFN-β) expression...
4.
Park Y, Jeong S, Lee H, Nam Y, Lee H, Lee Y, et al.
Toxics
. 2024 Nov;
12(11).
PMID: 39590956
Polyhexamethylene guanidine phosphate (PHMG-p), a major ingredient of humidifier disinfectants, is known to induce inflammation, interstitial pneumonitis, and fibrosis in the lungs. While its histopathologic toxicities have been studied in...
5.
Lee H, Jeong S, Baek Y, Lee H, Sa J, Lee J, et al.
Chemosphere
. 2024 Nov;
368:143785.
PMID: 39577803
Polyhexamethylene guanidine (PHMG) is widely utilized in personal hygiene products due to its bactericidal, non-volatile, and hydrophilic properties. However, the long-term toxic effects and underlying mechanisms associated with respiratory exposure...
6.
Park Y, Kim H, Kim J, Lee J, Kim Y, Lim J, et al.
Ecotoxicol Environ Saf
. 2024 Nov;
287:117222.
PMID: 39520742
In this study, we investigated the potential mechanisms by which polyhexamethylene guanidine phosphate (PHMG-p), a known respiratory irritant, may contribute to lung cancer development. Using the adverse outcome pathway (AOP)...
7.
Kim D, Shin Y, Baek Y, Kang H, Lim J, Bae O
J Toxicol Environ Health A
. 2024 Oct;
88(4):137-151.
PMID: 39446036
The mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one (CMIT/MIT) is a biocide widely used as a preservative in various commercial products. This biocide has also been used as an active ingredient in...
8.
Kim D, Shin Y, Park J, Lim D, Choi H, Choi S, et al.
Chemosphere
. 2024 Aug;
364:143010.
PMID: 39098349
Dosimetry modeling and point of departure (POD) estimation using in vitro data are essential for mechanism-based hazard identification and risk assessment. This study aimed to develop a putative adverse outcome...
9.
Kim H, Kim J, Lee J, Kim Y, Lim J, Baek Y, et al.
Epidemiol Health
. 2024 Jul;
46:e2024060.
PMID: 39026433
Objectives: Exposure to humidifier disinfectants has been linked to respiratory diseases, including interstitial lung disease, asthma, and pneumonia. Consequently, numerous toxicological studies have explored respiratory damage as both a necessary...
10.
Jeong S, Lee H, Nam Y, Kang J, Lee H, Choi J, et al.
Sci Rep
. 2024 Mar;
14(1):7178.
PMID: 38531959
Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated associations between PHMG-p dose and...