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Yong-Sheng Gong

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Articles 40
Citations 228
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Recent Articles
1.
Yan W, Cai J, Wang J, Gong Y, Ding X
Neoplasma . 2022 Mar; 69(3):648-656. PMID: 35330996
Clinical trials suggest that non-small-cell lung cancer (NSCLC) patients with KRAS mutations and wild-type EGFR have reduced benefits from gefitinib treatment. Ferroptosis is a new form of cell death that...
2.
Xue F, Wang H, Xu S, Liu S, Gong Y, Fan X
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2021 Nov; 37(6):589-593. PMID: 34821089
To investigate the protective effects of L-carnitine (LC) on lipopolysaccharide (LPS) - injured mouse pulmonary microvascular endothelial cells (PMVECs) and its effects on autophagy and apoptosis. Cultured mouse PMVECs were...
3.
Liu L, Shan X, Zhang F, Fan X, Fan J, Wang Y, et al.
Int J Mol Med . 2020 Oct; 46(6):2235-2250. PMID: 33125123
The roles of the Hippo‑Yes‑associated protein (YAP) pathway in lung injury and repair remain elusive. The present study examined the effects of systemic inhibition or stimulation of YAP activity on...
4.
Hao J, Xu L, Huang T, Yu Y, Wang Y, Fan X, et al.
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2020 Jan; 35(5):414-417. PMID: 31894672
Objective: To investigate the effects of apolipoprotein E (apoE) on the proliferation of pulmonary arterial smooth muscle cells (PASMCs) induced by hypoxia. Methods: Primary culture of mouse PASMCs was prepared...
5.
Liu Z, Zhang Y, Wang X, Fan X, Zhang Y, Li X, et al.
Biomed Pharmacother . 2019 Jul; 118:109227. PMID: 31351433
Endothelial-to-mesenchymal transition (EndMT) is closely related to the pathogenesis of various diseases, including cardiac fibrosis. Transforming growth factor (TGF)-β1 strongly induces EndMT, and sirtuin 1 (SIRT1) may play vital roles...
6.
Liu L, Huang T, Hao J, Chen R, Fan X, Gong Y, et al.
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2019 Apr; 34(6):492-495. PMID: 31032582
Objective: To observe the changes of apolipoprotein E (apoE) protein expression of pulmonary tissue in mice with pulmonary hypertension induced by hypoxia. Methods: The animal model of hypoxic pulmonary hypertension...
7.
Chen R, Jiang P, Liu L, Gao Y, Yang X, Cai Z, et al.
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2018 Jun; 33(6):493-496. PMID: 29931896
Objective: To observe the role of apelin in the prevention of pulmonary hypertension induced by hypoxia in mice. Methods: Adult male apoE gene knockout (apoE-KO) mice were exposed to isobaric...
8.
Ding L, Zheng Q, Li Y, Chen X, Chen R, Wang X, et al.
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2018 Jun; 32(3):214-218. PMID: 29931879
Objective: To investigate the roles of catestatin (CST) in 2-kidney-1 clip (2K1C)-induced renal hypertension in rats, and to explore the underlying mechanism. Methods: Thirty six male SD rats were randomly...
9.
Fan F, Shen W, Zheng Q, Gao Y, Hu K, Fan X, et al.
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2018 Jun; 32(5):463-465. PMID: 29931853
Objective: To observe the changes of lipid levels in mice with pulmonary hypertension induced by hypoxia. Methods: The animal model of hypoxic pulmonary hypertension was established by exposing the mice...
10.
Sang W, Zeng M, Chen S, Chen R, Fan X, Gong Y, et al.
Zhongguo Ying Yong Sheng Li Xue Za Zhi . 2018 Jun; 34(2):102-105. PMID: 29926670
Objectives: To investigate the role of autophagy inhibitor chloroquine (CQ) in acute ethanol-induced liver injury and its mechenism. Methods: Twenty-one C57BL/6 male mice were randomly divided into three groups:control group,...