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Yonatan Stelzer

Explore the profile of Yonatan Stelzer including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 2024
Followers 0
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Recent Articles
1.
Hadas R, Rubinstein H, Mittnenzweig M, Mayshar Y, Ben-Yair R, Cheng S, et al.
Nature . 2024 Sep; 634(8034):652-661. PMID: 39294373
The developing placenta, which in mice originates through the extraembryonic ectoderm (ExE), is essential for mammalian embryonic development. Yet unbiased characterization of the differentiation dynamics of the ExE and its...
2.
Dunjic M, Jonas F, Yaakov G, More R, Mayshar Y, Rais Y, et al.
Nat Commun . 2023 Jun; 14(1):3791. PMID: 37365167
Eviction of histones from nucleosomes and their exchange with newly synthesized or alternative variants is a central epigenetic determinant. Here, we define the genome-wide occupancy and exchange pattern of canonical...
3.
Mayshar Y, Raz O, Cheng S, Ben-Yair R, Hadas R, Reines N, et al.
Cell . 2023 May; 186(12):2610-2627.e18. PMID: 37209682
The hourglass model describes the convergence of species within the same phylum to a similar body plan during development; however, the molecular mechanisms underlying this phenomenon in mammals remain poorly...
4.
Cheng S, Mayshar Y, Stelzer Y
Cell . 2023 Feb; 186(4):683-685. PMID: 36803599
Transgenerational epigenetic inheritance in mammals has long been debatable. In this issue of Cell, Takahashi et al. induce DNA methylation at promoter-associated CpG islands (CGIs) of two metabolism-related genes and...
5.
Stelzer Y
Nat Rev Mol Cell Biol . 2023 Jan; 24(3):164. PMID: 36646751
No abstract available.
6.
Viukov S, Shani T, Bayerl J, Aguilera-Castrejon A, Oldak B, Sheban D, et al.
Stem Cell Reports . 2022 Oct; 17(11):2484-2500. PMID: 36270280
The recent derivation of human trophoblast stem cells (TSCs) from placental cytotrophoblasts and blastocysts opened opportunities for studying the development and function of the human placenta. Recent reports have suggested...
7.
Lau K, Rubinstein H, Gantner C, Hadas R, Amadei G, Stelzer Y, et al.
Cell Stem Cell . 2022 Sep; 29(10):1445-1458.e8. PMID: 36084657
Several in vitro models have been developed to recapitulate mouse embryogenesis solely from embryonic stem cells (ESCs). Despite mimicking many aspects of early development, they fail to capture the interactions...
8.
Cheng S, Mittnenzweig M, Mayshar Y, Lifshitz A, Dunjic M, Rais Y, et al.
Cell . 2022 Jul; 185(17):3169-3185.e20. PMID: 35908548
Mice deficient for all ten-eleven translocation (TET) genes exhibit early gastrulation lethality. However, separating cause and effect in such embryonic failure is challenging. To isolate cell-autonomous effects of TET loss,...
9.
Weinberg-Shukron A, Ben-Yair R, Takahashi N, Dunjic M, Shtrikman A, Edwards C, et al.
Nat Commun . 2022 Jul; 13(1):4391. PMID: 35906226
Mammalian parental imprinting represents an exquisite form of epigenetic control regulating the parent-specific monoallelic expression of genes in clusters. While imprinting perturbations are widely associated with developmental abnormalities, the intricate...
10.
Dierks D, Garcia-Campos M, Uzonyi A, Safra M, Edelheit S, Rossi A, et al.
Nat Methods . 2021 Sep; 18(9):1060-1067. PMID: 34480159
N-methyladenosine (m6A) is the most prevalent modification of messenger RNA in mammals. To interrogate its functions and dynamics, there is a critical need to quantify m6A at three levels: site,...