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Yohei Niikura

Explore the profile of Yohei Niikura including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 337
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Recent Articles
1.
Xi Y, Xu R, Chen S, Fang J, Duan X, Zhang Y, et al.
Cell Death Dis . 2024 Dec; 15(12):888. PMID: 39681555
No abstract available.
2.
Xi Y, Xu R, Chen S, Fang J, Duan X, Zhang Y, et al.
Cell Death Dis . 2024 Nov; 15(11):838. PMID: 39551802
Overexpression of mitotic arrest deficiency 2 (MAD2/MAD2L1), a pivotal component of the spindle assembly checkpoint (SAC), resulted in many types of cancer. Here we show that the depletion of tumor...
3.
Kitagawa R, Niikura Y, Becker A, Houghton P, Kitagawa K
Cell Rep . 2023 May; 42(6):112568. PMID: 37243594
The centromere is essential for ensuring high-fidelity transmission of chromosomes. CENP-A, the centromeric histone H3 variant, is thought to be the epigenetic mark of centromere identity. CENP-A deposition at the...
4.
Niikura Y, Fang L, Kitagawa R, Li P, Xi Y, You J, et al.
J Vis Exp . 2020 Jun; (160). PMID: 32597847
Studying the structure and the dynamics of kinetochores and centromeres is important in understanding chromosomal instability (CIN) and cancer progression. How the chromosomal location and function of a centromere (i.e.,...
5.
Niikura Y, Kitagawa R, Fang L, Kitagawa K
Dev Cell . 2019 Sep; 50(6):683-689.e6. PMID: 31550462
CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity, but how CENP-A is deposited at the centromere remains obscure. We previously reported that CENP-A K124 ubiquitylation, mediated...
6.
Niikura Y, Kitagawa R, Kitagawa K
Molecules . 2019 Jan; 24(3). PMID: 30678315
The centromere plays an essential role in accurate chromosome segregation, and the chromosomal location of the centromere is determined by the presence of a histone H3 variant, centromere protein A...
7.
Niikura Y, Kitagawa R, Ogi H, Kitagawa K
Cell Cycle . 2017 Aug; 16(18):1683-1694. PMID: 28816574
The centromere plays an essential role in accurate chromosome segregation, and defects in its function lead to aneuploidy and thus cancer. The centromere-specific histone H3 variant CENP-A is proposed to...
8.
Niikura Y, Kitagawa R, Kitagawa K
Dev Cell . 2017 Jan; 40(1):7-8. PMID: 28073011
No abstract available.
9.
Niikura Y, Kitagawa R, Kitagawa K
Mol Cell Oncol . 2016 Sep; 3(4):e1188226. PMID: 27652331
CENP-A (Centromere protein A) is a histone H3 variant that epigenetically determines the centromere position, but the mechanism of its centromere inheritance is obscure. We propose that CENP-A ubiquitylation, which...
10.
Niikura Y, Kitagawa R, Kitagawa K
Cell Rep . 2016 Apr; 15(1):61-76. PMID: 27052173
The presence of chromatin containing the histone H3 variant CENP-A dictates the location of the centromere in a DNA sequence-independent manner. But the mechanism by which centromere inheritance occurs is...