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Yohei Kirino

Explore the profile of Yohei Kirino including associated specialties, affiliations and a list of published articles. Areas
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Articles 166
Citations 4609
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Recent Articles
11.
Shigematsu M, Kawamura T, Deshpande D, Kirino Y
bioRxiv . 2024 Jul; PMID: 38948719
Chronic obstructive pulmonary disease (COPD) is the most prevalent lung disease, and macrophages play a central role in the inflammatory response in COPD. We here report a comprehensive characterization of...
12.
Adachi S, Kirino Y, Higashitani K, Hirahara L, Maeda A, Horita N, et al.
Rheumatol Adv Pract . 2024 Jun; 8(2):rkae065. PMID: 38854419
Objectives: To unravel the mechanisms underlying cell death in the vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome using peripheral blood samples and to assess the clinical value of this...
13.
Hirahara L, Kirino Y, Soejima Y, Iizuka Y, Yoshimi R, Fujieda Y, et al.
Front Immunol . 2024 Apr; 15:1354969. PMID: 38686380
Background: Little is known about the relationship between the disease activity of Behçet disease (BD) and the incidence of inflammatory major organ events. Objectives: In this prospective registry study, we...
14.
Pawar K, Kawamura T, Kirino Y
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2319569121. PMID: 38683985
Toll-like receptors (TLRs) are crucial components of the innate immune system. Endosomal TLR7 recognizes single-stranded RNAs, yet its endogenous ssRNA ligands are not fully understood. We previously showed that extracellular...
15.
Shirahama Y, Kokuzawa A, Yamauchi Y, Kirino Y, Nagai H, Inoue Y, et al.
Mod Rheumatol . 2024 Apr; 34(6):1213-1220. PMID: 38564322
Objectives: To define groups and characterize differences in the prognosis of patients with adult-onset Still's disease (AOSD). Methods: We performed a retrospective cohort study. Patients with AOSD were grouped using...
16.
Gumas J, Kawamura T, Shigematsu M, Kirino Y
Mol Ther Nucleic Acids . 2024 Mar; 35(1):102156. PMID: 38481936
(Mtb) infection is among the world's deadliest infectious diseases. Developing effective treatments and biomarkers for tuberculosis requires a deeper understanding of its pathobiology and host responses. Here, we report a...
17.
Kirino Y
Intern Med . 2024 Jan; 64(1):25-30. PMID: 38296470
Vacuoles, E1-ubiquitin-activating enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome, caused by an acquired mutation in the ubiquitin-activating enzyme ubiquitin-like modifier activating enzyme 1 (UBA1), was discovered in 2020. Since then, many...
18.
Fukuda N, Kanai D, Hoshino K, Fukuda Y, Morita R, Ishikawa Y, et al.
BMC Nephrol . 2024 Jan; 25(1):18. PMID: 38212709
Background: Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is caused by mutations in the ubiquitin-activating enzyme1 (UBA1) gene and characterised by an overlap between autoinflammatory and haematologic disorders. Case...
19.
Tsuchida N, Uchiyama Y, Maeda A, Horita N, Kirino Y, Matsumoto N
Rheumatology (Oxford) . 2023 Dec; 63(8):e229-e230. PMID: 38059601
No abstract available.
20.
Adachi S, Takase-Minegishi K, Maeda A, Nagai H, Horita N, Yoshimi R, et al.
Rheumatol Ther . 2023 Oct; 10(6):1623-1636. PMID: 37794210
Introduction: Patients with adult-onset Still's disease (AOSD) are at risk of developing macrophage activation syndrome (MAS), a life-threatening condition. Some cases of MAS have been reported following the use of...