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Yogita Ghodke

Explore the profile of Yogita Ghodke including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 173
Followers 0
Related Specialties
Public Health
Pharmacology
General Medicine
Top 10 Co-Authors
Kalpana Joshi
Bhushan Patwardhan
Arvind Chopra
Pooja Shintre
Aditi Chiplunkar
Xueyuan Cao
Varsha Gandhi
Jatinder K Lamba
Stanley Pounds
Peter L Anderson
Published In
Eur J Epidemiol
Indian J Med Res
Pharmacogenet Genomics
Clin Rheumatol
J Pharmacol Exp Ther
Affiliations
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Recent Articles
1.
PharmGKB summary: zidovudine pathway
Ghodke Y, Anderson P, Sangkuhl K, Lamba J, Altman R, Klein T
Pharmacogenet Genomics . 2012 Sep; 22(12):891-4. PMID: 22960662
No abstract available.
2.
Traditional medicine and genomics
Joshi K, Ghodke Y, Shintre P
J Ayurveda Integr Med . 2011 Aug; 1(1):26-32. PMID: 21829298
'Omics' developments in the form of genomics, proteomics and metabolomics have increased the impetus of traditional medicine research. Studies exploring the genomic, proteomic and metabolomic basis of human constitutional types...
3.
Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia
Mitra A, Crews K, Pounds S, Cao X, Feldberg T, Ghodke Y, et al.
J Pharmacol Exp Ther . 2011 Jun; 339(1):9-23. PMID: 21712425
Cytosolic 5'-nucleotidase II (NT5C2) is involved in the development of 1-β-d-arabinofuranosylcytosine (ara-C) resistance and has been associated with clinical outcome in patients receiving ara-C-based chemotherapy. NT5C2 inactivates ara-C by dephosphorylating...
4.
Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy Indians
Ghodke Y, Chopra A, Shintre P, Puranik A, Joshi K, Patwardhan B
Indian J Med Res . 2011 Mar; 133:274-9. PMID: 21441680
Background & Objectives: Many pharmacologically-relevant polymorphisms show variability among different populations. Though limited, data from Caucasian subjects have reported several single nucleotide polymorphism (SNPs) in folate biosynthetic pathway. These SNPs...
5.
Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic Variability
Ghodke Y, Joshi K, Patwardhan B
Evid Based Complement Alternat Med . 2009 Dec; 2011:249528. PMID: 20015960
Traditional Indian medicine-Ayurveda-classifies the human population into three major constituents or Prakriti known as Vata, Pitta and Kapha types. Earlier, we have demonstrated a proof of concept to support genetic...
6.
Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?
Ghodke Y, Chopra A, Joshi K, Patwardhan B
Clin Rheumatol . 2008 Feb; 27(6):787-9. PMID: 18274813
Methotrexate (MTX) is among the best-tolerated disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis (RA); major drawbacks of MTX therapy are the large interpatient variability in clinical response and...
7.
Genetic polymorphism of CYP2C19 in Maharashtrian population
Ghodke Y, Joshi K, Arya Y, Radkar A, Chiplunkar A, Shintre P, et al.
Eur J Epidemiol . 2007 Nov; 22(12):907-15. PMID: 17978853
Inter-individual variability in drug response is well known. Genetic polymorphism in genes encoding drug-metabolizing enzymes results in variation in drug metabolism and in turn drug response. The cytochrome P450 enzymes...
8.
HLA and disease
Ghodke Y, Joshi K, Chopra A, Patwardhan B
Eur J Epidemiol . 2005 Aug; 20(6):475-88. PMID: 16121756
Association of HLA and diseases is well known. Several population studies are available suggesting evidence of association of HLAs in more than 40 diseases. HLA found across various populations vary...