Yoelvis Garcia-Mesa
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Explore the profile of Yoelvis Garcia-Mesa including associated specialties, affiliations and a list of published articles.
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19
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985
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Recent Articles
1.
Rheinberger M, Costa A, Kampmann M, Glavas D, Shytaj I, Sreeram S, et al.
Cell Rep
. 2023 Feb;
42(2):112110.
PMID: 36790927
HIV-1 encounters the hierarchically organized host chromatin to stably integrate and persist in anatomically distinct latent reservoirs. The contribution of genome organization in HIV-1 infection has been largely understudied across...
2.
Sreeram S, Ye F, Garcia-Mesa Y, Nguyen K, El Sayed A, Leskov K, et al.
Trends Immunol
. 2022 Jul;
43(8):630-639.
PMID: 35840529
Despite potent suppression of HIV-1 viral replication in the central nervous system (CNS) by antiretroviral therapy (ART), between 15% and 60% of HIV-1-infected patients receiving ART exhibit neuroinflammation and symptoms...
3.
Ye F, Alvarez-Carbonell D, Nguyen K, Leskov K, Garcia-Mesa Y, Sreeram S, et al.
PLoS Pathog
. 2022 Jul;
18(7):e1010110.
PMID: 35797416
Human immune deficiency virus (HIV) infection in the brain leads to chronic neuroinflammation due to the production of pro-inflammatory cytokines, which in turn promotes HIV transcription in infected microglial cells....
4.
Garcia-Mesa Y, Xu H, Vance P, Gruenewald A, Garza R, Midkiff C, et al.
Antioxidants (Basel)
. 2021 Apr;
10(3).
PMID: 33803289
Dimethyl fumarate (DMF), an antioxidant/anti-inflammatory drug approved for the treatment of multiple sclerosis, induces antioxidant enzymes, in part through transcriptional upregulation. We hypothesized that DMF administration to simian immunodeficiency virus...
5.
Gruenewald A, Garcia-Mesa Y, Gill A, Garza R, Gelman B, Kolson D
J Neurovirol
. 2020 Sep;
26(6):846-862.
PMID: 32910432
Previous studies showed that persons living with HIV (PLWH) demonstrate higher brain prefrontal cortex neuroinflammation and immunoproteasome expression compared to HIV-negative individuals; these associate positively with HIV levels. Lower expression...
6.
Garcia-Mesa Y, Garza R, Diaz Ortiz M, Gruenewald A, Bastien B, Lobrovich R, et al.
J Virol
. 2020 Jul;
94(19).
PMID: 32669339
Brain injury occurs within days in simian immunodeficiency virus (SIV) or human immunodeficiency virus (HIV) infection, and some recovery may occur within weeks. Inflammation and oxidative stress associate with such...
7.
Garza R, Gill A, Bastien B, Garcia-Mesa Y, Gruenewald A, Gelman B, et al.
Neurol Neuroimmunol Neuroinflamm
. 2020 Apr;
7(3).
PMID: 32277015
Objective: To determine whether regulatory variations in the heme oxygenase-1 (HO-1) promoter (GT) dinucleotide repeat length could identify unique population genetic risks for neurocognitive impairment (NCI) in persons living with...
8.
Alvarez-Carbonell D, Ye F, Ramanath N, Garcia-Mesa Y, Knapp P, Hauser K, et al.
PLoS Pathog
. 2019 Dec;
15(12):e1008249.
PMID: 31887215
Despite effective antiretroviral therapy (ART), HIV-associated neurocognitive disorders (HAND) are found in nearly one-third of patients. Using a cellular co-culture system including neurons and human microglia infected with HIV (hμglia/HIV),...
9.
Alvarez-Carbonell D, Garcia-Mesa Y, Milne S, Das B, Dobrowolski C, Rojas R, et al.
Retrovirology
. 2017 Feb;
14(1):9.
PMID: 28166799
Background: Multiple toll-like receptors (TLRs) are expressed in cells of the monocytic lineage, including microglia, which constitute the major reservoir for human immunodeficiency virus (HIV) infection in the brain. We...
10.
Garcia-Mesa Y, Jay T, Checkley M, Luttge B, Dobrowolski C, Valadkhan S, et al.
J Neurovirol
. 2016 Nov;
23(1):47-66.
PMID: 27873219
The major reservoirs for HIV in the CNS are in the microglia, perivascular macrophages, and to a lesser extent, astrocytes. To study the molecular events controlling HIV expression in the...