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Yoe-Sik Bae

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Articles 164
Citations 2183
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Recent Articles
1.
Kim J, Hu W, Lee M, Bae G, Park J, Lee S, et al.
Immune Netw . 2025 Jan; 24(6):e45. PMID: 39801737
Sphingosylphosphorylcholine (SPC) is one of sphingomyelin-derived sphingolipids. SPC levels are increased in ascitic fluids of ovarian cancer patients and stratum corneum of atopic dermatitis (AD) patients. SPC has antitumor activity...
2.
Kim Y, Jeong Y, Bae G, Kang J, Lee M, Zabel B, et al.
Cell Mol Immunol . 2024 Feb; 21(4):349-361. PMID: 38311677
Distinct neutrophil populations arise during certain pathological conditions. The generation of dysfunctional neutrophils during sepsis and their contribution to septicemia-related systemic immune suppression remain unclear. In this study, using an...
3.
Park S, Kang J, Bae Y
Adv Biol Regul . 2023 Oct; 91:100988. PMID: 37845091
Phospholipase D (PLD) is an enzyme that catalyzes the hydrolysis of phosphatidylcholine into phosphatidic acid and free choline. In mammals, PLD exists in two well-characterized isoforms, PLD1 and PLD2, and...
4.
Kang J, Kim H, Park S, Kim Y, Bae Y
J Cell Mol Med . 2023 Aug; 27(18):2782-2791. PMID: 37603580
Obesity is a metabolic disorder that results from an imbalance of energy intake and consumption. As low-grade chronic inflammation caused by obesity can lead to various complications, it is important...
5.
Park B, Jeong Y, Hu W, Lee M, Kim J, Bae G, et al.
Front Immunol . 2023 Jul; 14:1151511. PMID: 37409121
Introduction: Multiple sclerosis (MS) is a potentially disabling disease that damages the brain and spinal cord, inducing paralysis of the body. While MS has been known as a T-cell mediated...
6.
Lee M, Lee S, Bae Y
Exp Mol Med . 2023 May; 55(6):1110-1130. PMID: 37258585
Sphingolipids, which are components of cellular membranes and organ tissues, can be synthesized or degraded to modulate cellular responses according to environmental cues, and the balance among the different sphingolipids...
7.
Lee M, Lee S, Bae Y
BMB Rep . 2022 Sep; 55(10):473-480. PMID: 36104260
Neutrophils, the most abundant innate immune cells, play essential roles in the innate immune system. As key innate immune cells, neutrophils detect intrusion of pathogens and initiate immune cascades with...
8.
Kim D, Na H, Cho K, Lee K, Choi J, Kwok S, et al.
Immunol Lett . 2022 Jun; 248:62-69. PMID: 35732207
Sjögren syndrome (SS) is an autoimmune disease in which immune cells infiltrate the exocrine gland. Since SS is caused by a disorder of the immune system, treatments should regulate the...
9.
Bae G, Kim Y, Park J, Lee M, Lee S, Kim J, et al.
Blood . 2022 Jun; 140(8):889-899. PMID: 35679477
Lung-resident neutrophils need to be tightly regulated to avoid degranulation- and cytokine-associated damage to fragile alveolar structures that can lead to fatal outcomes. Here we show that lung neutrophils (LNs)...
10.
Jeong Y, Huh S, Kim J, Park J, Lee C, Kim M, et al.
BMB Rep . 2022 Jun; 55(8):395-400. PMID: 35651330
Pseudomonas aeruginosa (P. aeruginosa) is a well-known Gramnegative opportunistic pathogen. Neutrophils play key roles in mediating host defense against P. aeruginosa infection. In this study, we identified a metabolite derived...