Yiyu Lu
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Explore the profile of Yiyu Lu including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
463
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Recent Articles
1.
Zhong X, Lu Y, Lin H, Wu Z, Luo Y, Ye Z, et al.
ACS Biomater Sci Eng
. 2025 Feb;
11(3):1660-1674.
PMID: 39953973
The impaired healing of alveolar bone defects in diabetic patients has attracted considerable attention, with Mogroside V (MV) emerging as a promising candidate due to its demonstrated antioxidation, hypoglycemic, and...
2.
Wang S, Kong Z, Shi Y, Shao C, Wang W, Su Z, et al.
J Med Chem
. 2024 May;
67(11):9447-9464.
PMID: 38748913
In this work, a series of bifunctional PD-L1/CD73 (cluster of differentiation 73) small-molecule inhibitors were designed and synthesized. Among them, showed the strongest PD-L1 inhibitory effects with an IC of...
3.
Cheng B, Shi Y, Shao C, Wang S, Su Z, Liu J, et al.
J Med Chem
. 2024 Apr;
67(8):6253-6267.
PMID: 38587857
In this work, a novel series of heterotricyclic DNA-PK inhibitors were rationally designed, synthesized, and assessed for their biological activity. In the DNA-PK biochemical assay, most compounds displayed potent enzymatic...
4.
Wang J, Hu Y, Zhao K, Fan J, Zhu J, Li Q, et al.
Front Biosci (Landmark Ed)
. 2024 Feb;
29(2):76.
PMID: 38420809
Background: Collagen-related cell adhesion molecules (CAMs) are a major component of the extracellular matrix (ECM) and often accumulate in the liver during chronic liver disease or hepatocellular carcinoma (HCC). In...
5.
Hu Y, Zhang X, Li Q, Zhou Q, Fang D, Lu Y
Comput Struct Biotechnol J
. 2023 Oct;
21:4619-4633.
PMID: 37817777
Hepatocellular carcinoma (HCC) is a malignant tumor with high mortality. This study aimed to build a prognostic signature for HCC patients based on immune-related genes (IRGs) and epigenetics-related genes (EPGs)....
6.
Lu Y, Zhao C, Wang C, Cai H, Hu Y, Chen L, et al.
J Ethnopharmacol
. 2023 Aug;
319(Pt 1):117092.
PMID: 37634751
Ethnopharmacological Relevance: Qingre Huashi (QRHS) formula is an empirical prescription for the treatment of Gan-Dan-Shi-Re syndrome (GDSR) syndrome in traditional Chinese medicine (TCM). GDSR is one of the typical TCM...
7.
Chen H, Liang W, Zheng W, Li F, Pan X, Lu Y
Aging (Albany NY)
. 2023 Aug;
15(16):7956-7973.
PMID: 37589509
Objective: Telomere-related genes (TRGs) play a critical role in various types of tumors. However, there is a lack of comprehensive exploration of their relevance in lung cancer. This research aimed...
8.
Ding Z, Wang S, Shi Y, Fei X, Cheng B, Lu Y, et al.
J Med Chem
. 2023 Jul;
66(15):10364-10380.
PMID: 37480153
In this work, we rationally designed, synthesized, and evaluated a series of novel d-(+)-biotin-conjugated PD-L1 inhibitors for targeted cancer therapy. Among them, exhibited the highest anti-PD-1/PD-L1 activity with an IC...
9.
Chen H, Liu X, He M, Gu W, Lu Y
J Int Med Res
. 2023 Jun;
51(6):3000605231177186.
PMID: 37387126
The most notable side-effect of apatinib, a novel antiangiogenic agent for the treatment of cancer, is hypertension, but there are few published studies regarding the use of apatinib to treat...
10.
Gu W, Zhang H, Lu Y, Li M, Yang S, Liang J, et al.
Cancer Res Treat
. 2023 Feb;
55(3):841-850.
PMID: 36791768
Purpose: We aimed to evaluate whether the addition of pemetrexed is effective in improving progression-free survival (PFS) in epidermal growth factor receptor (EGFR)-mutated patients with or without concomitant alterations. Materials...