Yixing Du
Overview
Explore the profile of Yixing Du including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
554
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Recent Articles
1.
Rigo M, Jin X, Godfrey L, Katz M, Sato H, Tomimatsu Y, et al.
Sci Rep
. 2024 Jul;
14(1):15574.
PMID: 38971867
The latest Triassic was characterised by protracted biotic extinctions concluding in the End-Triassic Extinction (~ 200 Ma) and a global carbon cycle perturbation. The onset of declining diversity is closely...
2.
Zhong S, Kiyoshi C, Du Y, Wang W, Luo Y, Wu X, et al.
Glia
. 2023 Jan;
71(4):1081-1098.
PMID: 36598109
Astrocytes are increasingly shown to operate as an isopotential syncytium in brain function. Protoplasmic astrocytes acquire this ability to functionally go beyond the single-cell level by evolving into a spongiform...
3.
Aten S, Du Y, Taylor O, Dye C, Collins K, Thomas M, et al.
Neurochem Res
. 2022 Jul;
48(4):1191-1210.
PMID: 35796915
Now astrocytes appear to be the key contributors to the pathophysiology of major depression. Evidence in rodents shows that chronic stress is associated with a decreased expression of astrocytic GFAP-immunoreactivity ...
4.
Du Y, Brennan F, Popovich P, Zhou M
Glia
. 2022 Apr;
70(7):1359-1379.
PMID: 35394085
Microglial control of activity-dependent plasticity and synaptic remodeling in neuronal networks has been the subject of intense research in the past several years. Although microglia-neuron interactions have been extensively studied,...
5.
Aten S, Kiyoshi C, Arzola E, Patterson J, Taylor A, Du Y, et al.
Prog Neurobiol
. 2022 Mar;
213:102264.
PMID: 35283239
The complexity of astrocyte morphology and syncytial coupling through gap junctions are crucial for astrocyte function in the brain. However, the ultrastructural details of astrocyte arborization and interactions between neighboring...
6.
Zhou M, Du Y, Aten S, Terman D
J Neurophysiol
. 2021 Sep;
126(4):1403-1419.
PMID: 34525325
Predominant expression of leak-type K channels provides astrocytes a high membrane permeability to K ions and a hyperpolarized membrane potential that are crucial for astrocyte function in brain homeostasis. In...
7.
Wang Q, Wang W, Aten S, Kiyoshi C, Du Y, Zhou M
Brain Sci
. 2020 Apr;
10(4).
PMID: 32252295
Astrocyte syncytial isopotentiality is a physiological mechanism resulting from a strong electrical coupling among astrocytes. We have previously shown that syncytial isopotentiality exists as a system-wide feature that coordinates astrocytes...
8.
Wang W, Kiyoshi C, Du Y, Taylor A, Sheehan E, Wu X, et al.
Mol Neurobiol
. 2019 Nov;
57(3):1332-1346.
PMID: 31728930
TREK-1, a two-pore-domain K channel, is highly expressed in the central nervous system. Although aberrant expression of TREK-1 is implicated in cognitive impairment, the cellular and functional mechanism underlying this...
9.
Kiyoshi C, Du Y, Zhong S, Wang W, Taylor A, Xiong B, et al.
Glia
. 2018 Oct;
66(12):2756-2769.
PMID: 30277621
Syncytial isopotentiality, resulting from a strong electrical coupling, emerges as a physiological mechanism that coordinates individual astrocytes to function as a highly efficient system in brain homeostasis. However, whether syncytial...
10.
Du Y, Wang W, Lutton A, Kiyoshi C, Ma B, Taylor A, et al.
Exp Neurol
. 2018 Feb;
303:1-11.
PMID: 29407729
Membrane potential (V) depolarization occurs immediately following cerebral ischemia and is devastating for the astrocyte homeostasis and neuronal signaling. Previously, an excessive release of extracellular K and glutamate has been...