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Yiren Zhou

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Articles 18
Citations 148
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Recent Articles
1.
Zhang X, Yang C, Zhang C, Wu J, Zhang X, Gao J, et al.
Nat Commun . 2025 Mar; 16(1):2174. PMID: 40038284
Mechanisms underlying functional axonal rewiring after adult mammalian central nervous system (CNS) injuries remain unclear partially due to limited models. Here we develop a mouse intracranial pre-olivary pretectal nucleus (OPN)...
2.
Feng C, Pan H, Zhang Y, Ye Z, Zhou Y, Zou H, et al.
J Pain Res . 2025 Jan; 18:341-352. PMID: 39867538
Background: Neuropathic pain (NP) is a prevalent chronic condition frequently accompanied by adverse emotional states. Previous research has demonstrated the clinical efficacy of electroacupuncture (EA) in mitigating neuropathic pain and...
3.
Li Y, Yang C, Fang S, Zhou Y, Li M, Liu Z, et al.
Adv Mater . 2024 Dec; :e2413957. PMID: 39648660
The ability to deliver protein therapeutics in a minimally invasive, safe, and sustained manner, without resorting to viral delivery systems, will be crucial for treating a wide range of chronic...
4.
Chen W, Wu J, Yang C, Li S, Liu Z, An Y, et al.
Proc Natl Acad Sci U S A . 2024 Sep; 121(39):e2404395121. PMID: 39292743
Adult central nervous system (CNS) neurons down-regulate growth programs after injury, leading to persistent regeneration failure. Coordinated lipids metabolism is required to synthesize membrane components during axon regeneration. However, lipids...
5.
Zhou Q, Li Y, Zhou Z, Zhou Y, Liu Y, Liu W, et al.
Curr Med Chem . 2024 Jun; PMID: 38939997
Tripartite-motif protein family member 65 (TRIM65) belongs to the tripartite motif (TRIM) protein family. Its typical structure consists of the RING, B-Box motif, and coiled-coil domains, which are highly conserved...
6.
Song Y, Zhao Z, Xu L, Huang P, Gao J, Li J, et al.
Dev Cell . 2024 Apr; 59(11):1396-1409.e5. PMID: 38569547
The ability of cells to perceive and respond to mechanical cues is essential for numerous biological activities. Emerging evidence indicates important contributions of organelles to cellular mechanosensitivity and mechanotransduction. However,...
7.
Xiao S, Qi M, Zhou Q, Gong H, Wei D, Wang G, et al.
Biomed Pharmacother . 2023 Dec; 170:116092. PMID: 38157642
Atherosclerosis significantly contributes to the development of cardiovascular diseases (CVD) and is characterized by lipid retention and inflammation within the artery wall. Multiple immune cell types are implicated in the...
8.
Alba M, Ebright B, Hua B, Slarve I, Zhou Y, Jia Y, et al.
Front Physiol . 2023 Feb; 14:1098467. PMID: 36818443
Liver cancer is a malignancy developed from underlying liver disease that encompasses liver injury and metabolic disorders. The progression from these underlying liver disease to cancer is accompanied by chronic...
9.
Wang X, Yang C, Wang X, Miao J, Chen W, Zhou Y, et al.
Neuron . 2022 Nov; 111(2):236-255.e7. PMID: 36370710
The coordination mechanism of neural innate immune responses for axon regeneration is not well understood. Here, we showed that neuronal deletion of protein tyrosine phosphatase non-receptor type 2 sustains the...
10.
Tu T, Alba M, Datta A, Hong H, Hua B, Jia Y, et al.
Front Oncol . 2022 Oct; 12:958696. PMID: 36276076
Obesity confers an independent risk for carcinogenesis. Classically viewed as a genetic disease, owing to the discovery of tumor suppressors and oncogenes, genetic events alone are not sufficient to explain...