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Yingqiong Cao

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Articles 14
Citations 303
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Recent Articles
1.
Xu W, Cao Y, Stephens S, Arredondo M, Chen Y, Perez W, et al.
JCI Insight . 2024 Jun; 9(11). PMID: 38855866
TANGO2-deficiency disorder (TDD) is an autosomal-recessive genetic disease caused by biallelic loss-of-function variants in the TANGO2 gene. TDD-associated cardiac arrhythmias are recalcitrant to standard antiarrhythmic medications and constitute the leading...
2.
Tatavosian R, Donovan M, Galbraith M, Duc H, Szwarc M, Joshi M, et al.
Cell Death Differ . 2023 Jan; 30(4):952-965. PMID: 36681780
The p53 transcription factor is a master regulator of cellular responses to stress that is commonly inactivated in diverse cancer types. Despite decades of research, the mechanisms by which p53...
3.
Knight W, Cao Y, Dillon P, Song K
STAR Protoc . 2021 Nov; 2(4):100912. PMID: 34755117
When cultured under typical conditions, human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are structurally and functionally immature. We have previously demonstrated that culture of hiPSC-CMs in maturation medium containing fatty acids,...
4.
Sun R, Shang W, Cao Y, Lan Y
BMC Public Health . 2021 Apr; 21(1):747. PMID: 33865357
Background: High-frequency hearing loss is a significant occupational health concern in many countries, and early identification can be effective for preventing hearing loss. The study aims to construct and validate...
5.
Knight W, Cao Y, Lin Y, Chi C, Bai B, Sparagna G, et al.
Stem Cell Reports . 2021 Feb; 16(3):519-533. PMID: 33636116
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a powerful platform for biomedical research. However, they are immature, which is a barrier to modeling adult-onset cardiovascular disease. Here, we sought...
6.
Riching A, Danis E, Zhao Y, Cao Y, Chi C, Bagchi R, et al.
J Mol Cell Cardiol . 2020 Dec; 153:44-59. PMID: 33359755
Direct reprogramming of fibroblasts into cardiomyocytes (CMs) represents a promising strategy to regenerate CMs lost after ischemic heart injury. Overexpression of GATA4, HAND2, MEF2C, TBX5, miR-1, and miR-133 (GHMT2m) along...
7.
Chi C, Leonard A, Knight W, Beussman K, Zhao Y, Cao Y, et al.
Proc Natl Acad Sci U S A . 2018 Dec; 116(2):556-565. PMID: 30584088
Mutations in lysosomal-associated membrane protein 2 () gene are associated with Danon disease, which often leads to cardiomyopathy/heart failure through poorly defined mechanisms. Here, we identify the LAMP-2 isoform B...
8.
Riching A, Zhao Y, Cao Y, Londono P, Xu H, Song K
J Vis Exp . 2018 Jun; (136). PMID: 29912202
Trans-differentiation of one somatic cell type into another has enormous potential to model and treat human diseases. Previous studies have shown that mouse embryonic, dermal, and cardiac fibroblasts can be...
9.
Zhao Y, Londono P, Cao Y, Sharpe E, Proenza C, ORourke R, et al.
Nat Commun . 2015 Sep; 6:8243. PMID: 26354680
Direct reprogramming of fibroblasts into cardiomyocytes by forced expression of cardiomyogenic factors, GMT (GATA4, Mef2C, Tbx5) or GHMT (GATA4, Hand2, Mef2C, Tbx5), has recently been demonstrated, suggesting a novel therapeutic...
10.
Cao Y, Wei J, Yang S, Sun J, Xu H, Wang Y, et al.
Protein Cell . 2014 Jun; PMID: 24962798
No abstract available.